CAJ | 학술논문

目的：探讨磁共振全身成像技术(WB-DWI)在良恶性淋巴结鉴别中的应用价值。方法收集2008年9月至2012年12月间43例经临床和病理证实的良性和恶性淋巴结肿大的患者和同期的20例健康志愿者分别行WB-DWI检查。分析良性、恶性淋巴结的WB-DWI表现和ADC值差异。结果健康志愿者WB-DWI淋巴结表现为类圆形或椭圆形较高信号，短径不超过1.0 cm，按照一定的解剖部位呈规律分布；ADC值(2.24±0.56)×10-3 mm2/s。良性淋巴结呈类圆形，短径不超过2.0 cm，较正常淋巴结信号增高，较少融合；平均ADC值(1.57±0.32)×10-3 mm2/s。恶性淋巴结不同程度增大、可融合，分布无规律；平均ADC值(1.57±0.32）×10-3 mm2/s。健康志愿者、良性和恶性淋巴结的ADC值之间差异均具有统计学意义(P<0.05)。结论 WB-DWI可以为初步鉴别良恶性淋巴结提供依据，尤其对于某些原发灶不明且伴有淋巴结转移的恶性肿瘤患者具有较大意义。
목적：탐토자공진전신성상기술(WB-DWI)재량악성림파결감별중적응용개치。방법수집2008년9월지2012년12월간43례경림상화병리증실적량성화악성림파결종대적환자화동기적20례건강지원자분별행WB-DWI검사。분석량성、악성림파결적WB-DWI표현화ADC치차이。결과건강지원자WB-DWI림파결표현위류원형혹타원형교고신호，단경불초과1.0 cm，안조일정적해부부위정규률분포；ADC치(2.24±0.56)×10-3 mm2/s。량성림파결정류원형，단경불초과2.0 cm，교정상림파결신호증고，교소융합；평균ADC치(1.57±0.32)×10-3 mm2/s。악성림파결불동정도증대、가융합，분포무규률；평균ADC치(1.57±0.32）×10-3 mm2/s。건강지원자、량성화악성림파결적ADC치지간차이균구유통계학의의(P<0.05)。결론 WB-DWI가이위초보감별량악성림파결제공의거，우기대우모사원발조불명차반유림파결전이적악성종류환자구유교대의의。
Objective To investigate the application value of whole-body magnetic resonance imaging (WB-DWI) in the identification of benign and malignant lymph nodes. Methods Twenty healthy volunteers and 43 patients confirmed as benign and malignant lymph nodes clinically and pathologically were collected, and performed WB-DWI examination scan from September 2008 to December 2012. The differences of WB-DWI and ADC values between benign and malignant lymph nodes were analyzed. Results The WB-DWI performance of lymph nodes in healthy volunteers showed class round or oval higher signal, with short diameter less than 1.0 cm and regular distribu-tion according to certain anatomical sites. The average ADC values was (2.24 ± 0.56) × 10-3 mm2/s. Benign lymph nodes showed class circular, with short diameter less than 2.0 cm, and its signs was higher than normal lymph node signal, with less fusion. The average ADC values was (1.57±0.32)×10-3 mm2/s. Malignant lymph nodes were enlarged to varied extent, with fusion and irregular distribution, and the average ADC values was (1.57±0.32)×10-3 mm2/s. There were sta-tistically significant differences in ADC values among healthy volunteers, benign and malignant lymph nodes (P<0.05). Conclusion WB-DWI scan can provide the basis for preliminary identification of benign and malignant lymph nodes, especially for some malignant tumors of unknown primary tumors associated with lymph node metastasis.