CAJ | 학술논문

目的：探讨不同时期应用胰岛素控制妊娠期糖尿病血糖对妊娠结局的影响。方法108例妊娠合并糖尿病患者在饮食治疗的基础上采用胰岛素治疗，其中56例胰岛素治疗时间为32孕周前(观察组)，52例胰岛素治疗时间为32孕周后(对照组)，观察不同时期应用胰岛素治疗对妊娠结局的影响。结果两组患者饮食疗法加胰岛素治疗后血糖基本控制在正常范围内。观察组妊娠期妊娠高血压综合征及其他并发症(羊水过多、胎盘早剥等)发生率均低于对照组，而早产率及剖宫产率明显高于对照组(P<0.05)，但观察组死产率及产后出血及感染发生率明显低于对照组(P<0.05)。观察组巨大儿、低体重儿、新生儿窒息、新生儿低血糖、红细胞增多症及高胆红素血症的发生率明显低于对照组(P<0.05)。结论32孕周前应用胰岛素控制妊娠期糖尿病血糖可改善母婴妊娠结局。
목적：탐토불동시기응용이도소공제임신기당뇨병혈당대임신결국적영향。방법108례임신합병당뇨병환자재음식치료적기출상채용이도소치료，기중56례이도소치료시간위32잉주전(관찰조)，52례이도소치료시간위32잉주후(대조조)，관찰불동시기응용이도소치료대임신결국적영향。결과량조환자음식요법가이도소치료후혈당기본공제재정상범위내。관찰조임신기임신고혈압종합정급기타병발증(양수과다、태반조박등)발생솔균저우대조조，이조산솔급부궁산솔명현고우대조조(P<0.05)，단관찰조사산솔급산후출혈급감염발생솔명현저우대조조(P<0.05)。관찰조거대인、저체중인、신생인질식、신생인저혈당、홍세포증다증급고담홍소혈증적발생솔명현저우대조조(P<0.05)。결론32잉주전응용이도소공제임신기당뇨병혈당가개선모영임신결국。
Objective To explore the effects of using insulin in different pregnant periods to control diabe-tes blood sugar on pregnancy outcome during pregnant period. Methods One hundred and eight patients with dia-betes in pregnancy used insulin and diet control to control diabetes blood sugar. The insulin therapy time of 52 cases was before 32 gestational weeks (the observation group), and that of 56 cases was after 32 gestational weeks (the control group). The pregnancy outcome of the two groups were observed. Results The blood sugar of the patients in the two groups was in normal range after diet control and insulin therapy. The incidence of pregnancy-induced hy-pertension syndrome during pregnancy and other complications (polyhydramnios, placental abruption) of the obser-vation group were significantly lower than that of the control group (P<0.05), while the incidence of preterm birth and the cesarean delivery in the observation group were significantly higher than that of the control group (P<0.05). The incidence of the stillbirth and postpartum hemorrhage and infection were significantly higher (P<0.05). The inci-dence of macrosomia, low birth weight, neonatal asphyxia, neonatal hypoglycemia, disease of grow in quantity of red blood cells and high blood bilirubin of the observation group were significantly lower than that of the control group (P<0.05). Conclusion Using insulin to control diabetes blood sugar before 32 gestational weeks could im-prove the outcome of the maternal and infant.