医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
34期
160-160
,共1页
支原体肺炎%儿童%肺功能%嗜酸性粒细胞%变化
支原體肺炎%兒童%肺功能%嗜痠性粒細胞%變化
지원체폐염%인동%폐공능%기산성립세포%변화
Mycoplasma pneumoniae pneumonia%Children%Lung function%Eosinophil%Change
目的：观察儿童肺炎支原体肺炎(MPP)的常规肺功能和血嗜酸性粒细胞(EOS)比例的变化规律,并探讨其临床意义。方法采用JEAGER公司生产的MasterScreen IOS肺功能仪检测22例MPP急性期、恢复期患儿和50例门诊健康体检儿童的常规肺功能,以及检测血EOS%,并加以比较。结果22例MPP患儿急性期肺功能检查中有3例(13.64%)肺通气功能大致正常,其余19例(86.36%)有不同程度的肺功能损害,表现为小气道病变有10例(45.45%),阻塞性通气功能障碍有2例(9.09%),限制性通气功能障碍6例(27.27%),混合性通气功能障碍1例(4.55%)。恢复期仍有4例(18.18%)表现为轻度限制性通气功能障碍,10例(45.45%)表现为小气道病变,其余肺功能恢复正常(36.36%)。健康对照组无1例肺通气功能检查异常。 MPP恢复期儿童血EOS%显著高于急性期及健康儿童(P<0.05)。结论 MPP患儿存在EOS血症,急性期大小气道通气功能均有损害,恢复期除用力肺活量占预计值百分比(FVC/Pred%)恢复正常外,其他指标仍显著低于正常组。我们认为动态观察MPP患儿肺功能和血EOS变化,对判断儿童MPP预后有一定临床意义。
目的：觀察兒童肺炎支原體肺炎(MPP)的常規肺功能和血嗜痠性粒細胞(EOS)比例的變化規律,併探討其臨床意義。方法採用JEAGER公司生產的MasterScreen IOS肺功能儀檢測22例MPP急性期、恢複期患兒和50例門診健康體檢兒童的常規肺功能,以及檢測血EOS%,併加以比較。結果22例MPP患兒急性期肺功能檢查中有3例(13.64%)肺通氣功能大緻正常,其餘19例(86.36%)有不同程度的肺功能損害,錶現為小氣道病變有10例(45.45%),阻塞性通氣功能障礙有2例(9.09%),限製性通氣功能障礙6例(27.27%),混閤性通氣功能障礙1例(4.55%)。恢複期仍有4例(18.18%)錶現為輕度限製性通氣功能障礙,10例(45.45%)錶現為小氣道病變,其餘肺功能恢複正常(36.36%)。健康對照組無1例肺通氣功能檢查異常。 MPP恢複期兒童血EOS%顯著高于急性期及健康兒童(P<0.05)。結論 MPP患兒存在EOS血癥,急性期大小氣道通氣功能均有損害,恢複期除用力肺活量佔預計值百分比(FVC/Pred%)恢複正常外,其他指標仍顯著低于正常組。我們認為動態觀察MPP患兒肺功能和血EOS變化,對判斷兒童MPP預後有一定臨床意義。
목적：관찰인동폐염지원체폐염(MPP)적상규폐공능화혈기산성립세포(EOS)비례적변화규률,병탐토기림상의의。방법채용JEAGER공사생산적MasterScreen IOS폐공능의검측22례MPP급성기、회복기환인화50례문진건강체검인동적상규폐공능,이급검측혈EOS%,병가이비교。결과22례MPP환인급성기폐공능검사중유3례(13.64%)폐통기공능대치정상,기여19례(86.36%)유불동정도적폐공능손해,표현위소기도병변유10례(45.45%),조새성통기공능장애유2례(9.09%),한제성통기공능장애6례(27.27%),혼합성통기공능장애1례(4.55%)。회복기잉유4례(18.18%)표현위경도한제성통기공능장애,10례(45.45%)표현위소기도병변,기여폐공능회복정상(36.36%)。건강대조조무1례폐통기공능검사이상。 MPP회복기인동혈EOS%현저고우급성기급건강인동(P<0.05)。결론 MPP환인존재EOS혈증,급성기대소기도통기공능균유손해,회복기제용력폐활량점예계치백분비(FVC/Pred%)회복정상외,기타지표잉현저저우정상조。아문인위동태관찰MPP환인폐공능화혈EOS변화,대판단인동MPP예후유일정림상의의。
Objective To observe the changes of lung function and the perentage of blood eosinophil (EOS)in children with mycoplasma pneumoniae pneumonia (MPP).Methods The general pulmonary function and blood EOS%of 22 children with MPP during the acute and convalescent phase and 50 healthy children were tested.Results The general pulmonary function of 22 children with MPP during the acute phase were reported that 3 cases(13.94%)were normal and 19 cases(86.36%)were abnormal.Among them 10 cases(45.45%)had smal airway dysfunction,2 cases(9.09%)had obstructive ventilatory disturbance,6 cases (27.27%)had restricted ventilatory disturbance,1 case (13.64%)had mixed ventilatory disturbance.During the convalescent phase,4 cases had light restricted ventilatory disturbance,10 cases had smal airway dysfunction,others were normal.None of the healthy children had abnormal report.During the acute phase,FEV1%pred,FVC%pred,FEF50%pred,FEF75%pred, MMEF%pred were significantly lower than the healthy children.In convalescent phase,FVC%pred was normal,other indexes were stil lower than healthy children.The EOS%in MPP group during the convalescent phase were higher than the acute phase and the healthy children.Conclusion MPP can result in EOS inflammation and impaired pulmonary function,especial y obstruction in smal airway.
