CAJ | 학술논문

目的：探讨幽门螺旋杆菌（Heliobacter pylori,HP）与寻常痤疮发病以及严重程度的关系。方法：选择2013年6月～2014年2月至医院就诊的轻中度寻常痤疮患者216例为观察组，同时选取体检中心90名健康体检人员为对照组，检测两组的HP感染情况，并对观察组中合并感染的患者进行HP根治治疗，观察患者痤疮程度的改变。结果：观察组共计HP感染患者165例，感染率76.4%，对照组HP感染者39例，感染率43.3%，两组比较差异有统计学意义（χ2=31.238，P＜0.001）。对观察组中HP感染患者给予HP根治治疗，114例治疗成功（A组），51例治疗失败（B组），8周后A组62例痤疮严重程度出现改善，有效率54.4%，B组14例改善，有效率34.1%，两组改善率比较差异有统计学意义（χ2=4.943，P＜0.05）。结论：HP与寻常痤疮的发生存在关联，但与寻常痤疮的严重程度无关，给予抗HP治疗后，可以减轻寻常痤疮的严重程度。
목적：탐토유문라선간균（Heliobacter pylori,HP）여심상좌창발병이급엄중정도적관계。방법：선택2013년6월～2014년2월지의원취진적경중도심상좌창환자216례위관찰조，동시선취체검중심90명건강체검인원위대조조，검측량조적HP감염정황，병대관찰조중합병감염적환자진행HP근치치료，관찰환자좌창정도적개변。결과：관찰조공계HP감염환자165례，감염솔76.4%，대조조HP감염자39례，감염솔43.3%，량조비교차이유통계학의의（χ2=31.238，P＜0.001）。대관찰조중HP감염환자급여HP근치치료，114례치료성공（A조），51례치료실패（B조），8주후A조62례좌창엄중정도출현개선，유효솔54.4%，B조14례개선，유효솔34.1%，량조개선솔비교차이유통계학의의（χ2=4.943，P＜0.05）。결론：HP여심상좌창적발생존재관련，단여심상좌창적엄중정도무관，급여항HP치료후，가이감경심상좌창적엄중정도。
Objective: To explore the correlation between the Helicobacter pylori infection and the acne vulgaris. Methods: Totally 216 patients who were treated in the hospital were chosen as the observation group while 90 health examination customers without acne or gastric symptoms were set as the control group. The incidence of H. pylori infection was observed. The patients complicated with H. pylori infection in the observation group received the eradication of H. pylori, and the improvement of acne was observed. Results: The H. pylori infection occurred in 165 cases in the observation group with the infection rate of 76.4% and in 39 cases in the control group with the infection rate of 43.3%, the difference between the two groups was statistically significant (P<0.001). Conclusion: There is a certain correlation between the H. pylori infection with onset of acne, but there is no relationship with the degree of acne. The treatment of H. pylori can reduce the degree of acne.