CAJ | 학술논문

目的：研究中药治疗流感的临床效果。方法检索2013年12月31日以前在MEDLINE、EMBASE、CBM-disk、CNKI全文数据库以及万方中文期刊全文数据库公开发表的有关流感治疗的文献。结果最终纳入7篇随机对照临床研究。荟萃分析的结果显示，银翘散组方加减与奥司他韦在退热[ WMD ＝5．66，95％CI （－32．02，43．35）， P＝0．77]和病毒核酸阴转[WMD＝－6．21，95％CI （－84．19，71．76）， P＝0．88]方面的效果相似；连花清瘟胶囊在病毒核酸阴转方面与奥司他韦相似[WMD＝－0．24，95％CI （－4．79，4．31）， P＝0．92]，但在退热方面的效果要优于奥司他韦[WMD＝－4．65，95％CI （－8．91，－0．38）， P＝0．03]。结论中药在抗流感病毒感染方面具有积极作用。
목적：연구중약치료류감적림상효과。방법검색2013년12월31일이전재MEDLINE、EMBASE、CBM-disk、CNKI전문수거고이급만방중문기간전문수거고공개발표적유관류감치료적문헌。결과최종납입7편수궤대조림상연구。회췌분석적결과현시，은교산조방가감여오사타위재퇴열[ WMD ＝5．66，95％CI （－32．02，43．35）， P＝0．77]화병독핵산음전[WMD＝－6．21，95％CI （－84．19，71．76）， P＝0．88]방면적효과상사；련화청온효낭재병독핵산음전방면여오사타위상사[WMD＝－0．24，95％CI （－4．79，4．31）， P＝0．92]，단재퇴열방면적효과요우우오사타위[WMD＝－4．65，95％CI （－8．91，－0．38）， P＝0．03]。결론중약재항류감병독감염방면구유적겁작용。
Objective To justify the clinical use of traditional Chinese materia medica (TCMM) in the treatment of influenza.Methods The literature on treatment of influenza published before December 31, 2013 was searched in MEDLINE, EMBASE, CBMdisk, Chinese National Knowledge Infrastructure (CNKI) and Wanfang Database.Results A total of 7 randomized controlled trials were identified and reviewed. Based on the meta-analysis, Yinqiao Powder prescription had similar effect to oseltamivir in defervescence [WMD=5.66, 95%CI (-32.02, 43.35), P=0.77] and viral shed-ding [WMD=-6.21, 95%CI (-84.19, 71.76), P=0.88], and Lianhuaqingwen also had similar effect in viral shed-ding [WMD=-0.24, 95%CI (-4.79, 4.31), P=0.92] but was more effective in defervescence [WMD=-4.65, 95%CI (-8.91, -0.38), P=0.03].Conclusion TCMM has a potential positive effect in the treatment of influenza.