中外女性健康（下半月）
中外女性健康（下半月）
중외녀성건강（하반월）
CHINESE-FOREIGN WOMEN'S HEALTH
2014年
10期
188-189,195
,共3页
非酒精性脂肪性肝病%2型糖尿病%危险因素%腹型肥胖
非酒精性脂肪性肝病%2型糖尿病%危險因素%腹型肥胖
비주정성지방성간병%2형당뇨병%위험인소%복형비반
Type 2 diabetes mellitus%Non-alcoholic fatty liver disease%Risk factors%Abdominal obesity
目的：比较非酒精性脂肪性肝病（NAFLD）与2型糖尿病（T2DM）的临床特征差异并探讨分析相关危险因素。方法：选取在厦门大学附属中山医院就诊的老年人共837人，分为单纯2型糖尿病组（T2DM组），单纯非酒精性脂肪性肝病组（NAFLD组），非酒精性脂肪性肝病合并2型糖尿病组（ND组）及无DM及NAFLD组（对照组）。所有个体均检测身高、体重、腰围、血压、血糖、血脂、尿酸、肝脏B超。结果：DM、NAFLD及ND组中高血压、糖尿病、高脂血症、高尿酸血症的患病率人数比例均高于对照组。ND组腰围、BMI、血压、TC及TG、空腹血糖均显著高于NAFLD组或T2DM组。腰围及BMI为3组共同的独立危险因素（OR波动于1.05～1.58），而TG为NAFLD及ND两组的共同独立危险因素（OR波动于1.52～3.19）。结论：2型糖尿病合并非酒精性脂肪肝患者存在更严重的肥胖倾向和代谢紊乱，严重的腹型肥胖及TG升高为同时患DM及NAFLD人群的最强危险因素。
目的：比較非酒精性脂肪性肝病（NAFLD）與2型糖尿病（T2DM）的臨床特徵差異併探討分析相關危險因素。方法：選取在廈門大學附屬中山醫院就診的老年人共837人，分為單純2型糖尿病組（T2DM組），單純非酒精性脂肪性肝病組（NAFLD組），非酒精性脂肪性肝病閤併2型糖尿病組（ND組）及無DM及NAFLD組（對照組）。所有箇體均檢測身高、體重、腰圍、血壓、血糖、血脂、尿痠、肝髒B超。結果：DM、NAFLD及ND組中高血壓、糖尿病、高脂血癥、高尿痠血癥的患病率人數比例均高于對照組。ND組腰圍、BMI、血壓、TC及TG、空腹血糖均顯著高于NAFLD組或T2DM組。腰圍及BMI為3組共同的獨立危險因素（OR波動于1.05～1.58），而TG為NAFLD及ND兩組的共同獨立危險因素（OR波動于1.52～3.19）。結論：2型糖尿病閤併非酒精性脂肪肝患者存在更嚴重的肥胖傾嚮和代謝紊亂，嚴重的腹型肥胖及TG升高為同時患DM及NAFLD人群的最彊危險因素。
목적：비교비주정성지방성간병（NAFLD）여2형당뇨병（T2DM）적림상특정차이병탐토분석상관위험인소。방법：선취재하문대학부속중산의원취진적노년인공837인，분위단순2형당뇨병조（T2DM조），단순비주정성지방성간병조（NAFLD조），비주정성지방성간병합병2형당뇨병조（ND조）급무DM급NAFLD조（대조조）。소유개체균검측신고、체중、요위、혈압、혈당、혈지、뇨산、간장B초。결과：DM、NAFLD급ND조중고혈압、당뇨병、고지혈증、고뇨산혈증적환병솔인수비례균고우대조조。ND조요위、BMI、혈압、TC급TG、공복혈당균현저고우NAFLD조혹T2DM조。요위급BMI위3조공동적독립위험인소（OR파동우1.05～1.58），이TG위NAFLD급ND량조적공동독립위험인소（OR파동우1.52～3.19）。결론：2형당뇨병합병비주정성지방간환자존재경엄중적비반경향화대사문란，엄중적복형비반급TG승고위동시환DM급NAFLD인군적최강위험인소。
Objective:To investigate the clinical features and risk factors of non-alcoholic fatty liver disease (NAFLD) vs type 2 diabetes mellitus(T2DM).Methods:The subjects were assigned to four groups :those only with T2DM(MS);those only withN AFLD (NAFLD);those with both of the two diseases (ND);those with neither of the two diseases (control).Questionnairea bout medical record ,diet,sport and family history was conducted,and fast plasma sugar,lipid profile,body mass index (BMI),waist circumference(WC) as well as blood pressure was measured. Diagnosis of NAFLD was based on the criteria suggested by Chinese Society of Hepatology, and that of T2DM following the 2010 American ADA criteria.Results:The prevalence of hypertension ,diabetes,hyperlipemia and hyperuricemia was higher in T2DM ,NAFLD and ND than that in control group.The blood pressure ,waist circumference,BMI,fast blood sugar,TC and TG were significantly increased in ND group as compared with those in NAFLD group or T2DM group.All of the three groups of NAFLD,T2DM and ND shared the common independent risk factors which were waist circumference and BMI (OR=1.05~1.58).Conclusion:Type-2 diabetic patients with NAFLD usually had serious obesity and metabolic disorder.Both of the abdominal obesity and hypertriglyceridemia were strong predictors of NAFLD with T2DM.
