CAJ | 학술논문

【目的】比较阴道超声引导下抽吸减胎术联合局部甲氨蝶呤（MTX）注射与经腹部超声引导下孕囊内注射M TX治疗子宫切口妊娠（CSP）的疗效。【方法】分析2010年1月至2014年4月本院收治的子宫下段剖宫产后CSP共67例患者的临床资料。67例患者分为试验组和对照组，其中试验组（24例）行阴道超声引导下抽吸减胎术联合局部M TX注射；对照组（43例）经腹部超声引导下孕囊内注射M TX ，比较两组的临床疗效。【结果】试验组患者在术中术后出血量、住院时间、住院费用、转开腹手术等方面明显优于对照组，且两组比较差异有显著性（P ＜0．05），两组患者清宫手术时间比较差异无统计学意义（P ＞0．05）。【结论】阴道超声引导下抽吸减胎术联合局部 M TX注射治疗CSP明显优于经腹部超声引导下孕囊内注射M TX。
【목적】비교음도초성인도하추흡감태술연합국부갑안접령（MTX）주사여경복부초성인도하잉낭내주사M TX치료자궁절구임신（CSP）적료효。【방법】분석2010년1월지2014년4월본원수치적자궁하단부궁산후CSP공67례환자적림상자료。67례환자분위시험조화대조조，기중시험조（24례）행음도초성인도하추흡감태술연합국부M TX주사；대조조（43례）경복부초성인도하잉낭내주사M TX ，비교량조적림상료효。【결과】시험조환자재술중술후출혈량、주원시간、주원비용、전개복수술등방면명현우우대조조，차량조비교차이유현저성（P ＜0．05），량조환자청궁수술시간비교차이무통계학의의（P ＞0．05）。【결론】음도초성인도하추흡감태술연합국부 M TX주사치료CSP명현우우경복부초성인도하잉낭내주사M TX。
[Objective] To compare the efficacy between transvaginal B‐type ultrasound‐guided aspiration embryo reduction plus local injection of methotrexate (M TX) and abdominal B‐type ultrasound‐guided M TX in‐jection in gestation sac for the treatment of cesarean scar pregnancy (CSP). [Methods]Clinical date of 67 pa‐tients with low CSP of in our hospital from Jan. 2010 to April 2014 were analyzed respectively. All patients were randomly divided into experimental group and control group. The experimental group( n = 24) under‐went transvaginal B‐type ultrasound‐guided aspiration embryo reduction plus local injection of MTX, while the control group( n=43) was given abdominal B‐type ultrasound‐guided MTX injection in gestation sac. Clinical efficacy was compared between two groups. [Results] Some aspects such as postoperative blood loss, hospi‐talization time, hospitalization cost and conversion into laparotomy in experimental group were much better than the control group, and there were significant differences between two groups( P <0. 05), but there was no significant difference in uterine curettage time between two groups(P>0. 05). [Conclusion]Transvaginal B‐type ultrasound‐guided aspiration embryo reduction plus local injection of M TX for the treatment of CSP is much superior to abdominal B‐type ultrasound‐guided M TX injection in gestation sac.