CAJ | 학술논문

【目的】探讨微波辅助照射治疗结核性胸膜炎的疗效。【方法】选取结核性胸膜炎患者97例，根据治疗方法分为治疗组和对照组，两组均给予相同的抗结核方案，即3HRZE／6HR ，并行胸腔置管，注射无菌的利福平针剂；治疗组在此基础上加用微波局部照射治疗，每次照射15 min ，每日2次，治疗4周；比较两组胸膜厚度、用力肺活量（FVC ）、第1秒用力呼气容积（FEV1）、肺总量（T LC ）等指标。【结果】治疗组、对照组胸水分别在（12．4±3．1）d、（18．5±4．2）d消失；治疗组胸膜厚度、FVC （％）、FEV1（％）、T LC （％）分别为（1．21±0．35）mm、（87．5±7．30）、（87．4±6．4）、（88．3±3．6），与对照组（1．96±0．56）mm、（79．3±7．4）、（78．3±5．6）、（79．3±4．2）比较均有统计学意义（P＜0．05）；而两组不良反应和复发率比较无统计学差异（P ＞0．05）。【结论】在规范抗结核基础上，采用微波辅助局部照射治疗结核性胸膜炎操作方便、疗效显著，值得临床推广应用。
【목적】탐토미파보조조사치료결핵성흉막염적료효。【방법】선취결핵성흉막염환자97례，근거치료방법분위치료조화대조조，량조균급여상동적항결핵방안，즉3HRZE／6HR ，병행흉강치관，주사무균적리복평침제；치료조재차기출상가용미파국부조사치료，매차조사15 min ，매일2차，치료4주；비교량조흉막후도、용력폐활량（FVC ）、제1초용력호기용적（FEV1）、폐총량（T LC ）등지표。【결과】치료조、대조조흉수분별재（12．4±3．1）d、（18．5±4．2）d소실；치료조흉막후도、FVC （％）、FEV1（％）、T LC （％）분별위（1．21±0．35）mm、（87．5±7．30）、（87．4±6．4）、（88．3±3．6），여대조조（1．96±0．56）mm、（79．3±7．4）、（78．3±5．6）、（79．3±4．2）비교균유통계학의의（P＜0．05）；이량조불량반응화복발솔비교무통계학차이（P ＞0．05）。【결론】재규범항결핵기출상，채용미파보조국부조사치료결핵성흉막염조작방편、료효현저，치득림상추엄응용。
[Objective] To observe the clinical effect of adjuvant microwave irradiation for the treatment of tuberculous pleurisy .[Methods] Totally 97 patients with tuberculous pleurisy were chosen .According the treatment methods ,all patients were divided into treatment group and control group .Both groups were given the same anti‐tuberculosis program 3HRZE/6HR together with intubation in thoracic cavity and injection of sterile rifampicin .The treatment group was additionally given local irradiation of microwave .Each irradiation time was 15min ,and the irradiation lasted twice a day for 4 weeks .Pleura thickness ,forced vital capacity (FVC) ,forced expiratory volume in one second (FEV1) and total lung capacity (TLC) were compared between 2 groups .[Results] Pleural effusion in both groups disappeared at (12 .4 ± 3 .1) d、(18 .5 ± 4 .2)d .Pleural thickness ,FVC(% ) ,FEV1(% ) and TLC(% ) in treatment group were (1 .21 ± 0 .35)mm ,(87 .5 ± 7 .30) , (87 .4 ± 6 .4) and (88 .3 ± 3 .6) respectively ,and there were significant differences between the treatment group and control group [(1 .96 ± 0 .56)mm ,(79 .3 ± 7 .4) ,(78 .3 ± 5 .6) and (79 .3 ± 4 .2)]( P < 0 .05) . There was no significant difference in adverse reaction and recurrence between two groups ( P>0 .05) .[Con‐clusion]Local irradiation with microwave is an effective treatment of tuberculous pleurisy and worthy of clinical promotion .