CAJ | 학술논문

目的：对比研究溃疡性结肠炎(UC)与克罗恩病(CD)的病理形态学特点。方法：将诊断为UC和CD的181例患者病例资料进行回顾性分析，根据实验室与临床资料，比较其镜下及组织学表现的不同。结果：经过结肠镜下比较发现，病变部位、分布状态、纵行溃疡、环形溃疡、阿弗他溃疡、结节样增生、肠腔狭窄及鹅卵石征等项目在两组患者间的比较其差异显著，而其他类型则无差异。两组患者的病理结果比较发现，炎症侵犯肌层、绒毛状结构增生、隐窝炎或脓肿、非干酪性肉芽肿、隐窝扭曲、杯状细胞减少以及潘氏细胞化生等项目组间差异显著。结论：根据UC和CD的病理学特点，在诊断UC和CD时需要将内镜下和显微镜下结肠病变的特征进行综合分析，以便做出更为准确的诊断。
목적：대비연구궤양성결장염(UC)여극라은병(CD)적병리형태학특점。방법：장진단위UC화CD적181례환자병례자료진행회고성분석，근거실험실여림상자료，비교기경하급조직학표현적불동。결과：경과결장경하비교발현，병변부위、분포상태、종행궤양、배형궤양、아불타궤양、결절양증생、장강협착급아란석정등항목재량조환자간적비교기차이현저，이기타류형칙무차이。량조환자적병리결과비교발현，염증침범기층、융모상결구증생、은와염혹농종、비간락성육아종、은와뉴곡、배상세포감소이급반씨세포화생등항목조간차이현저。결론：근거UC화CD적병이학특점，재진단UC화CD시수요장내경하화현미경하결장병변적특정진행종합분석，이편주출경위준학적진단。
Objective:Comparative study on ulcerative colitis and Crohn's disease pathological features.Methods: The March 2009 to February 2012 in our hospital diagnostics to clinical data of patients with ulcerative colitis and Crohn's disease were analyzed retrospectively, based on my medical record system to extract the hospital laboratory and clinical data of patients with the study, comparison of endoscopic and histological its different manifestations.Results:After comparing colonoscopy found lesions, distribution, longitudinal ulcers, circular ulcers, aphthous ulcers, nodular hyperplasia, intestinal symptoms such narrow cobblestone projects with significant differences between the two groups of patients in comparison, whereas no significant difference in other types. To compare the two groups of patients with pathological results found violations of the muscle inflammation, villous structures hyperplasia, crypt inflammation or abscess, non-caseating granulomas, crypt distortion, goblet cells decreased, the Paneth cell metaplasia and other project team the difference was significant, with statistical significance. Conclusion: Endoscopic features of colonic lesions under the microscope and the need to conduct a comprehensive analysis in the diagnosis of ulcerative colitis and Crohn's disease, and in order to make a more accurate diagnosis.