中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2014年
11期
90-92
,共3页
胎膜早破%解脲支原体%沙眼衣原体%药敏试验
胎膜早破%解脲支原體%沙眼衣原體%藥敏試驗
태막조파%해뇨지원체%사안의원체%약민시험
Premature rupture of membranes (PROM)%Uu%Ct%Susceptibility testing
目的:了解胎膜早破孕妇生殖道支原体和衣原体感染及耐药性,为临床孕妇支原体和衣原体筛查及治疗提供依据。方法:选取胎膜早破孕产妇368例,由妇产科医师取其宫颈口内2cm 左右处宫颈分泌物进行 Uu 和 Ct 检测及药敏试验,观察检测及药敏试验结果。结果:368例胎膜早破患者中,病原体阳性率为78.26%(288/368),其中,Uu 单一感染55.82%(205/368),Ct 单一感染5.98%(22/368),Uu +Mh感染4.08%(15/368),Uu +Ct 感染7.61%(28/368)、Uu +Mh +Ct 感染0.82%(3/368),Uu 感染率为68.21%(251/368),Ct 感染率为14.40%(53/368);药敏结果显示,Uu 对强力霉素和米诺环素耐药率为0,对交沙霉素耐药率为3.41%,对四环素耐药率为22.93%,对红霉素等大环内酯类耐药率均超过50%,对诺氟沙星等喹诺酮类耐药率为40%~50%左右;Ct 对强力霉素及米诺环素耐药率为4.55%,对四环素耐药率为22.73%,对交沙霉素耐药率为31.82%,对其他大环内酯类及喹诺酮类耐药率均超过50%;Uu +Ct 混合感染时,耐药性与 Uu 和 Ct 单一感染时类似,但耐药率均有所升高,尤其对米诺环素及强力霉素耐药率升高最为明显。结论:胎膜早破孕产妇生殖道中支原体的高检出率及 Ct 检出率提示其与胎膜早破密切相关,临床治疗时可选择四环素类,可首选交沙霉素、米诺环素、强力霉素。
目的:瞭解胎膜早破孕婦生殖道支原體和衣原體感染及耐藥性,為臨床孕婦支原體和衣原體篩查及治療提供依據。方法:選取胎膜早破孕產婦368例,由婦產科醫師取其宮頸口內2cm 左右處宮頸分泌物進行 Uu 和 Ct 檢測及藥敏試驗,觀察檢測及藥敏試驗結果。結果:368例胎膜早破患者中,病原體暘性率為78.26%(288/368),其中,Uu 單一感染55.82%(205/368),Ct 單一感染5.98%(22/368),Uu +Mh感染4.08%(15/368),Uu +Ct 感染7.61%(28/368)、Uu +Mh +Ct 感染0.82%(3/368),Uu 感染率為68.21%(251/368),Ct 感染率為14.40%(53/368);藥敏結果顯示,Uu 對彊力黴素和米諾環素耐藥率為0,對交沙黴素耐藥率為3.41%,對四環素耐藥率為22.93%,對紅黴素等大環內酯類耐藥率均超過50%,對諾氟沙星等喹諾酮類耐藥率為40%~50%左右;Ct 對彊力黴素及米諾環素耐藥率為4.55%,對四環素耐藥率為22.73%,對交沙黴素耐藥率為31.82%,對其他大環內酯類及喹諾酮類耐藥率均超過50%;Uu +Ct 混閤感染時,耐藥性與 Uu 和 Ct 單一感染時類似,但耐藥率均有所升高,尤其對米諾環素及彊力黴素耐藥率升高最為明顯。結論:胎膜早破孕產婦生殖道中支原體的高檢齣率及 Ct 檢齣率提示其與胎膜早破密切相關,臨床治療時可選擇四環素類,可首選交沙黴素、米諾環素、彊力黴素。
목적:료해태막조파잉부생식도지원체화의원체감염급내약성,위림상잉부지원체화의원체사사급치료제공의거。방법:선취태막조파잉산부368례,유부산과의사취기궁경구내2cm 좌우처궁경분비물진행 Uu 화 Ct 검측급약민시험,관찰검측급약민시험결과。결과:368례태막조파환자중,병원체양성솔위78.26%(288/368),기중,Uu 단일감염55.82%(205/368),Ct 단일감염5.98%(22/368),Uu +Mh감염4.08%(15/368),Uu +Ct 감염7.61%(28/368)、Uu +Mh +Ct 감염0.82%(3/368),Uu 감염솔위68.21%(251/368),Ct 감염솔위14.40%(53/368);약민결과현시,Uu 대강력매소화미낙배소내약솔위0,대교사매소내약솔위3.41%,대사배소내약솔위22.93%,대홍매소등대배내지류내약솔균초과50%,대낙불사성등규낙동류내약솔위40%~50%좌우;Ct 대강력매소급미낙배소내약솔위4.55%,대사배소내약솔위22.73%,대교사매소내약솔위31.82%,대기타대배내지류급규낙동류내약솔균초과50%;Uu +Ct 혼합감염시,내약성여 Uu 화 Ct 단일감염시유사,단내약솔균유소승고,우기대미낙배소급강력매소내약솔승고최위명현。결론:태막조파잉산부생식도중지원체적고검출솔급 Ct 검출솔제시기여태막조파밀절상관,림상치료시가선택사배소류,가수선교사매소、미낙배소、강력매소。
Objectives:To understand the status of hemycoplasma and chlamydia infection and drug resist-ance of reproductive tract of pregnant women with premature rupture of membranes (PROM),providing basis for clinical mycoplasma and chlamydia screening and treatment.Methods:368 pregnant women with PROM were se-lected to conduct Uu and Ct detection and susceptibility testing,and the results were recorded.Results:The patho-gens positive rate of all 368 pregnant women was 78.26% (288 /368),including 55.82% (205 /368)of Uu single infection,5.98% (22 /368)of Ct single infection,4.08% (15 /368)of Uu +Mh infection,7.61% (28 /368)of Uu +Ct infection,0.82% (3 /368)of Uu +Mh +Ct infection,68.21% (251 /368)of Uu infection and 14. 40% (53 /368)of Ct infection;as the susceptibility results showed,the resistance of Uu against doxycycline and minocycline was 0,3.41% for josamycin,22.93 % for tetracycline,over 50% for erythromycin and other macroli-de and about 40% -50% for norfloxacin quinolone;while the resistance rate of Ct was 4.55% for doxycycline and minocycline,22.73% for tetracycline,31.82% for josamycin,and over 50% for other macrolides and quinolones;in mixed infection of Uu +Ct,the drug resistance was similar with increased resistance rate,especially for minocy-cline and doxycycline.Conclusion:The high detection rate of mycoplasma and Ct suggest it is closely associated with PROM and tetracyclines especially josamycine,minocycline and doxycycline are preferred for clinical treat-ment.