CAJ | 학술논문

目的：探讨短时受精后不同脱颗粒时间对体外受精胚胎移植周期的影响。方法：将行常规 IVF治疗患者的同周期卵子分为两组（除去完全受精失败以及受精率低下的治疗周期），即短时受精即刻脱颗粒细胞组（A 组：精卵孵育4h 后即刻脱颗粒细胞）和短时受精并次日晨脱颗粒细胞组（B 组：精卵孵育4h 并受精后17～18h 脱颗粒细胞），比较两组的受精率（2 PN 率）、多精受精率（多 PN 率）、卵裂率、优胚率、胚胎利用率、临床妊娠率。结果：两组的受精率（2 PN 率）、多精受精率（多 PN 率）、卵裂率、优胚率、胚胎利用率、临床妊娠率之间差异无统计学意义。结论：精卵孵育4h 后去除颗粒细胞对受精、胚胎发育没有显著影响。
목적：탐토단시수정후불동탈과립시간대체외수정배태이식주기적영향。방법：장행상규 IVF치료환자적동주기란자분위량조（제거완전수정실패이급수정솔저하적치료주기），즉단시수정즉각탈과립세포조（A 조：정란부육4h 후즉각탈과립세포）화단시수정병차일신탈과립세포조（B 조：정란부육4h 병수정후17～18h 탈과립세포），비교량조적수정솔（2 PN 솔）、다정수정솔（다 PN 솔）、란렬솔、우배솔、배태이용솔、림상임신솔。결과：량조적수정솔（2 PN 솔）、다정수정솔（다 PN 솔）、란렬솔、우배솔、배태이용솔、림상임신솔지간차이무통계학의의。결론：정란부육4h 후거제과립세포대수정、배태발육몰유현저영향。
Objectives:To explore the effects of different degranulation cells time on in vitro fertilization and embryo transfer cycles after short -term fertilization.Methods:The oocytes in the same IVF -ET cycle were divided into two groups (cycles with fertilization failure or low fertilization rate were not included).Group A (short-term fertilization and immediate degranulation,gamete co -incubating for 4 hours,then removing all degranula-tion cells),group B (short -term fertilization and degranulation in the morning on the next day,gamete co -incu-bating for 4 hours,then removing all degranulation cells 17 -18 hours after insemination).The fertilization rate (two pronucleus rate),the polyspermy rate (multiple pronucleus rate),the cleavage rate,the good quality embryo rate,the embryo utilization rate and the pregnancy rate of the two groups were compared.Results:There was no statistically difference in the fertilization rate (two pronucleus rate),the polyspermy rate (multiple pronucleus rate),the cleavage rate,the good quality embryo rate,the embryo utilization rate and the pregnancy rate among the two groups.Conclusion:Degranulation cells removal after gamete co -incubating for 4 hours has no effect on ferti-lization,embryo development and embryo implantation.