国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2014年
1期
36-38
,共3页
肠道病毒感染%1型糖尿病
腸道病毒感染%1型糖尿病
장도병독감염%1형당뇨병
Enterovirus infection%Type 1 diabetes
1型糖尿病的发病机制复杂.作为环境因素之一的感染因素,肠道病毒感染与1型糖尿病密切相关.肠道病毒感染易感个体后,通过直接感染和引起自身免疫反应两种方式损伤β细胞,从而导致胰岛功能损伤,胰岛素分泌障碍,临床出现糖尿病,最终导致胰岛功能衰竭.
1型糖尿病的髮病機製複雜.作為環境因素之一的感染因素,腸道病毒感染與1型糖尿病密切相關.腸道病毒感染易感箇體後,通過直接感染和引起自身免疫反應兩種方式損傷β細胞,從而導緻胰島功能損傷,胰島素分泌障礙,臨床齣現糖尿病,最終導緻胰島功能衰竭.
1형당뇨병적발병궤제복잡.작위배경인소지일적감염인소,장도병독감염여1형당뇨병밀절상관.장도병독감염역감개체후,통과직접감염화인기자신면역반응량충방식손상β세포,종이도치이도공능손상,이도소분비장애,림상출현당뇨병,최종도치이도공능쇠갈.
The pathogenesis of type 1 diabetes is complicated.The infection of enterovirus is closely related to this disease as one of the environmental factors.After susceptible individuals are infected by enterovirus,beta cells in pancreas islets are damaged in two ways,direct infection and autoimmune responses,then leading to the decrease of insulin secretion,clinical diabetes,finally resulting in functional failure of pancreatic islet.
