CAJ | 학술논문

尿毒症是各种肾病终末期的转归，肾移植术是目前治疗尿毒症的最佳方案，但由于不同个体免疫组织相容性复合物不同，往往在移植术后发生各种类型的排斥反应，严重影响移植肾的功能和受者的生活质量，所以临床需要一种高特异性、高敏感性的生物学标志物早期预示排斥反应发生的高危性，从而让临床医生能够更改治疗方案，避免移植物的损害。近些年，越来越多的关于这类生物学标志物的研究已经开展。
뇨독증시각충신병종말기적전귀，신이식술시목전치료뇨독증적최가방안，단유우불동개체면역조직상용성복합물불동，왕왕재이식술후발생각충류형적배척반응，엄중영향이식신적공능화수자적생활질량，소이림상수요일충고특이성、고민감성적생물학표지물조기예시배척반응발생적고위성，종이양림상의생능구경개치료방안，피면이식물적손해。근사년，월래월다적관우저류생물학표지물적연구이경개전。
Uremia is the terminal outcome of all kinds of nephropathy. Renal transplantation is the best solu-tion in the treatments of uremia. However, due to different individual immune histocompatibility, different types of re-jection may occur after transplantation which would severely affect the life quality of recipients and the function of transplant kidney. So, biological markers with high specificity and sensitivity are clinically called to indicate the risk of rejections at early phase. In that case, physicians can change their treatments so as to protect transplants. In recent years, more and more researches on this field have been carried out.