海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
19期
2845-2848
,共4页
宫外发育迟缓%低出生体重早产儿%胎龄%呼吸窘迫综合征
宮外髮育遲緩%低齣生體重早產兒%胎齡%呼吸窘迫綜閤徵
궁외발육지완%저출생체중조산인%태령%호흡군박종합정
Extrauterine growth restriction%Low birth weight preterm%Gestational age%RDS
目的：探讨胎龄≤32周低出生体重早产儿宫外发育迟缓(EUGR)发生率及其相关影响因素。方法纳入126例胎龄≤32周低出生体重早产儿，记录胎龄(超声或出生时成熟度分析数据)、出生时体重、身长、头围、性别、是否低于胎龄儿、是否存在呼吸窘迫综合征、最大生理性体重减少率、恢复出生体重的天数、起始肠内喂养时间、完全肠内喂养时间(每天奶量>100 ml/kg·d)，37~42周时测定早产儿体重、身长、头围，以体重、身长和头围计，分析EUGR发生率、其危险因素以及适于胎龄儿(AGA)和低于胎龄儿(SGA) EUGR发生率。结果 EUGR组胎龄、出生体重、出生身长、出生头围均低于非EUGR组(均P<0.01)，而体重下降率(%)、恢复出生体重时间、起始肠内喂养时间以及完全肠内喂养时间均大于非EUGR组(均P<0.01)，SGA比例明显大于非EUGR组(均P<0.05)。以体重、身长、头围计，所有新生儿EUGR发生率分别为47.6%、39.7%和4.8%。总体上SGA宫外发育迟缓率明显高于AGA (均P<0.01)。胎龄、恢复出生体重时间、完全肠内喂养时间与EUGR发生密切相关。结论胎龄、宫内发育迟缓、营养摄入差及呼吸窘迫综合症仍是胎龄≤32周早产儿EUGR发生的危险因素。
目的：探討胎齡≤32週低齣生體重早產兒宮外髮育遲緩(EUGR)髮生率及其相關影響因素。方法納入126例胎齡≤32週低齣生體重早產兒，記錄胎齡(超聲或齣生時成熟度分析數據)、齣生時體重、身長、頭圍、性彆、是否低于胎齡兒、是否存在呼吸窘迫綜閤徵、最大生理性體重減少率、恢複齣生體重的天數、起始腸內餵養時間、完全腸內餵養時間(每天奶量>100 ml/kg·d)，37~42週時測定早產兒體重、身長、頭圍，以體重、身長和頭圍計，分析EUGR髮生率、其危險因素以及適于胎齡兒(AGA)和低于胎齡兒(SGA) EUGR髮生率。結果 EUGR組胎齡、齣生體重、齣生身長、齣生頭圍均低于非EUGR組(均P<0.01)，而體重下降率(%)、恢複齣生體重時間、起始腸內餵養時間以及完全腸內餵養時間均大于非EUGR組(均P<0.01)，SGA比例明顯大于非EUGR組(均P<0.05)。以體重、身長、頭圍計，所有新生兒EUGR髮生率分彆為47.6%、39.7%和4.8%。總體上SGA宮外髮育遲緩率明顯高于AGA (均P<0.01)。胎齡、恢複齣生體重時間、完全腸內餵養時間與EUGR髮生密切相關。結論胎齡、宮內髮育遲緩、營養攝入差及呼吸窘迫綜閤癥仍是胎齡≤32週早產兒EUGR髮生的危險因素。
목적：탐토태령≤32주저출생체중조산인궁외발육지완(EUGR)발생솔급기상관영향인소。방법납입126례태령≤32주저출생체중조산인，기록태령(초성혹출생시성숙도분석수거)、출생시체중、신장、두위、성별、시부저우태령인、시부존재호흡군박종합정、최대생이성체중감소솔、회복출생체중적천수、기시장내위양시간、완전장내위양시간(매천내량>100 ml/kg·d)，37~42주시측정조산인체중、신장、두위，이체중、신장화두위계，분석EUGR발생솔、기위험인소이급괄우태령인(AGA)화저우태령인(SGA) EUGR발생솔。결과 EUGR조태령、출생체중、출생신장、출생두위균저우비EUGR조(균P<0.01)，이체중하강솔(%)、회복출생체중시간、기시장내위양시간이급완전장내위양시간균대우비EUGR조(균P<0.01)，SGA비례명현대우비EUGR조(균P<0.05)。이체중、신장、두위계，소유신생인EUGR발생솔분별위47.6%、39.7%화4.8%。총체상SGA궁외발육지완솔명현고우AGA (균P<0.01)。태령、회복출생체중시간、완전장내위양시간여EUGR발생밀절상관。결론태령、궁내발육지완、영양섭입차급호흡군박종합증잉시태령≤32주조산인EUGR발생적위험인소。
Objective To investigate the incidence and related factors of extrauterine growth retardation (EUGR) in low birth weight preterm children. Methods A total of 126 cases of low birth weight premature children with gestational age≤32 week were enrolled, and gestational age (ultrasound or birth maturity analysis of data), birth weight, length, head circumference, gender, the existence of respiratory distress syndrome, the maximum physiologi-cal weight reduction rate, the number of days to regain birth weight, the time for starting enteral feeding and full enter-al feeding (daily milk>100 ml/kg·d) were recorded. During 37~42 weeks, weight, length, head circumference, body weight, length and head circumference of premature children were measured. Incidence of EUGR and risk factors, and incidences of EUGR in appropriate for gestational age children (AGA) and small for gestational age children (SGA) were analyzed. Results The gestational age, birth weight, birth length, and head circumference at birth of EUGR group were lower than those of the non-EUGR group (all P<0.01), while the rate of weight loss (%), time to regain birth weight, time for starting enteral feeding and giving full enteral feeding were greater than those of non-EUGR group (all P<0.01). The proportion of SGA was significantly greater than that of non-EUGR group (all P<0.05). Based on weight, length, head circumference, incidences of EUGR in all newborns were 47.6%, 39.7%and 4.8%. Toatally, extrauterine growth retardation rate of SGA was significantly higher than that of AGA (all P<0.01).Gestational age, birth weight, recovery time, and time for full enteral feeding were closely related with EUGR. Conclusion Gestation-al age, intrauterine growth retardation, poor nutritional intake and RDS are still the risk factors of EUGR in premature children with gestational age≤32 week.
