CAJ | 학술논문

BACKGROUND:?Hepatocellular?carcinoma?is?the?most?common?type? of? primary? liver? tumor? and? its? incidence? is? increasing?worldwide.?The?study?aimed?to?compare?patients?subjected?to?liver?resection?or?radiofrequency?ablation. <br> METHODS:??One?hundred?and?forty?cirrhotic?patients?in?stage?A? or? B? of? Child-Pugh? with? single? nodular? or? multinodular?hepatocellular? carcinoma? were? included? in? this? retrospective?study.? Among? them,? 87? underwent? surgical? resection,? and? 53?underwent?percutaneous?radiofrequency?ablation.?Patient?charac-teristics,?survival,?and?recurrence-free?survival?were?analyzed. <br> RESULTS:?Recurrence-free?survival?was?longer?in?the?resection?group?in?comparison?to?the?radiofrequency?group?with?a?median?recurrence-free?time?of?36?versus?26?months,?respectively?(P=0.01,?HR=1.52,? 95%? CI:? 1.05-2.25).? In? the? resection? group,? median?survival? was? 46? months,? with? the? 1-,? 3-? and? 5-year? survival?rates?of?89.7%,?72.4%?and?40.2%.?In?the?radiofrequency?group,?median? survival? was? 32? months,? with? the? 1-,? 3-? and? 5-year?survival?rates?of?83.0%,?43.4%?and?22.6%?(P<0.01). <br> CONCLUSIONS:?Surgical?resection?improves?the?overall?survival?and?recurrence-free?survival?in?comparison?with?radiofrequency?ablation.?New?evidences?are?needed?to?define?the?real?role?of?the?percutaneous?technique?as?an?alternative?to?surgery.