CAJ | 학술논문

BACKGROUND:?The? indocyanine? green? (ICG)? retention?test? is? the? most? popular? liver? function? test? for? selecting?patients?for?major?hepatectomy.?Traditionally,?it?is?done?using?spectrophotometry?with?serial?blood?sampling.?The?newly-developed?pulse?spectrophotometry?is?a?faster?alternative,?but?its?accuracy?on?Child-Pugh?A?cirrhotic?patients?undergoing?hepatectomy?for?hepatocellular?carcinoma?has?not?been?well?documented.?This?study?aimed?to?assess?the?accuracy?of?the?LiMON?,?one?of?the?pulse?spectrophotometry?systems,?in?measuring?preoperative?ICG?retention?in?these?patients?and?to?devise?an?easy?formula?for?conversion?of?the?results?so?that?they?can?be?compared?with?classical?literature?records?where?ICG?retention?was?measured?by?the?traditional?method. <br> METHODS:?We?measured?the?liver?function?of?70?Child-Pugh?A? cirrhotic? patients? before? hepatectomy? for? hepatocellular?carcinoma?from?September?2008?to?January?2009.?ICG?retention?at? 15? minutes? measured? by? traditional? spectrophotometry?(ICGR15)?was?compared?with?ICG?retention?at?15?minutes?measured?by?the?LiMON?(ICGR15(L)). <br> RESULTS:?The?median?ICGR15?was?14.7%?(5.6%-32%)?and?the?median?ICGR15(L)?was?10.4%?(1.2%-28%).?The?mean?difference?between?them?was?-4.3606.?There?was?a?strong?correlation? between? ICGR15? and? ICGR15(L)? (correlation?coefifcient,?0.844;?95%?conifdence?interval,?0.762-0.899).?The?following?formula?was?devised:?ICGR15=1.16×ICGR15(L)+2.73. <br> CONCLUSIONS:?The?LiMON?provides?a?fast?and?repeatable?way?to?measure?ICG?retention?at?15?minutes,?but?with?constant?underestimation?of?the?real?value.?Therefore,?when?comparing?results? obtained? by? traditional? spectrophotometry? and? the?LiMON,?adjustment?of?results?from?the?latter?is?necessary,?and?this?can?be?done?with?a?simple?mathematical?calculation?using?the?above?formula.