CAJ | 학술논문

目的：评价应用无创正压通气治疗慢性阻塞性肺疾病导致肺性脑病的临床效果。方法：采用回顾性研究方法，观察68例COPD导致呼吸衰竭患者使用双水平无创呼吸机辅助通气，动态观察比较治疗前和治疗后动脉血气及相关临床指标。结果：68例患者中有50例治疗好转后出院，8例需要行气管插管机械通气，10例放弃治疗，有效率为73．53％。结论：无创正压通气对部分慢性阻塞性肺疾病致肺性脑病的治疗有效，临床可酌情扩大无创正压通气的适应证，合理使用可避免早期气管插管机械通气治疗。
목적：평개응용무창정압통기치료만성조새성폐질병도치폐성뇌병적림상효과。방법：채용회고성연구방법，관찰68례COPD도치호흡쇠갈환자사용쌍수평무창호흡궤보조통기，동태관찰비교치료전화치료후동맥혈기급상관림상지표。결과：68례환자중유50례치료호전후출원，8례수요행기관삽관궤계통기，10례방기치료，유효솔위73．53％。결론：무창정압통기대부분만성조새성폐질병치폐성뇌병적치료유효，림상가작정확대무창정압통기적괄응증，합리사용가피면조기기관삽관궤계통기치료。
Objective:To evaluate the efficacies of non-invasive positive pressure ventilation (NIPPV) in treatment of chronic obstructive pulmonary dis-ease (COPD) complicated with pulmonary encephalopathy.Methods:A retrospective study was performed in 68 COPD patients with respiratory failure un-dergone NIPPV,and the arterial blood gas and related clinical indicators before and after treatment were dynamically observed and compared .Results:In the 68 cases,50 were recovered,8 required endotracheal intubation with mechanical ventilation,and 10 subjectively quitted the treatment.The effective rate was 73.53%.Conclusion:NIPPV can be effective for major COPD patients with pulmonary encephalopathy .Yet rational considerations shall be taken if it is applied to wider indications in order to eliminate early tracheal intubation and mechanical ventilation .