CAJ | 학술논문

目的：比较腹腔镜与开放手术治疗早期局限性前列腺癌的临床疗效及安全性。方法选择77例早期局限性前列腺癌患者，分为观察组40例和对照组37例，观察组采用腹腔镜前列腺癌根治术，对照组采用经耻骨后前列腺癌根治术，比较二者治疗效果。结果观察组患者手术时间与对照组相似，差异无统计学意义( P>0．05)；而术中出血量少于对照组，差异有统计学意义(P<0．05)。观察组患者引流管拔除时间和留置导尿时间与对照组相似，差异无统计学意义(P>0．05)；而观察组患者胃肠功能恢复时间、术后下床活动时间和术后住院时间均优于对照组，差异有统计学意义(P<0．05)。观察组术后并发症发生率30%，低于对照组的50%，差异有统计学意义(P<0．05)。两组患者术后1年及术后2年生化复发率相似，差异无统计学意义(P>0．05)。结论腹腔镜手术治疗局限性前列腺癌具有创伤小、恢复快、并发症少，而且在肿瘤控制方面与开放性手术具有相似的效果。
목적：비교복강경여개방수술치료조기국한성전렬선암적림상료효급안전성。방법선택77례조기국한성전렬선암환자，분위관찰조40례화대조조37례，관찰조채용복강경전렬선암근치술，대조조채용경치골후전렬선암근치술，비교이자치료효과。결과관찰조환자수술시간여대조조상사，차이무통계학의의( P>0．05)；이술중출혈량소우대조조，차이유통계학의의(P<0．05)。관찰조환자인류관발제시간화류치도뇨시간여대조조상사，차이무통계학의의(P>0．05)；이관찰조환자위장공능회복시간、술후하상활동시간화술후주원시간균우우대조조，차이유통계학의의(P<0．05)。관찰조술후병발증발생솔30%，저우대조조적50%，차이유통계학의의(P<0．05)。량조환자술후1년급술후2년생화복발솔상사，차이무통계학의의(P>0．05)。결론복강경수술치료국한성전렬선암구유창상소、회복쾌、병발증소，이차재종류공제방면여개방성수술구유상사적효과。
Objective In order to compare clinical effects and safety of laparoscope and open operation for treatment of early local prostate cancer. Methods 77 cases of patients with early local prostate cancer were selected in this study,they were distributed into the observation group 40 cases and control group 37 cases. The patients in the observation group were treated with laparoscopic radical prostatectomy,and the patients in the control group were treated with radical retropubic prostatectomy,thera-peutic effects of the two groups were compared. Results Operation time of the two groups was similar,the difference had no statis-tical significance( P>0. 05 ) , intraoperatve blood soss of the patients in the observation group was less than that in the control group,the difference had statistical significance(P<0. 05). Drainage tube removal time and indwelling catheter time of the patients in the observation group were similar to that in the control group,the differences had no statistical significance(P>0. 05). Gastro-intestinal function recovery time,postoperative activity time and postoperative hospitalization duration of the patients in the observa-tion group were superior to that in the control group. The differences had statistical significance ( P<0. 05 ) . Occurrence rate of postoperative complications in the observation group was 30%,while occurrence rate of postoperative complications in the control group was 50%,The difference had statistical significance(P<0. 05). In the observation group,biochemical recurrence rate of the patients within 1 year or two years after operation was similar to that in the control group,the difference had no statistical signifi-cance(P>0. 05). Conclusion Advantages of laparoscopic surgery for treatment of prostate cancer include low trauma,fast recov-ery,few complications,in addition,curative effects of laparoscopic surgery for tumor control were similar to that of open opera-tions.