CAJ | 학술논문

目的：研究广东省市售鳜和鲩体内孔雀石绿(malachite green, MG)与硝基呋喃类(nitrofurans, NFs)及其代谢物残留现状。方法111份鳜和鲩样品分别购自广州、深圳、佛山、中山、汕头和茂名等地,采用高效液相色谱-串联质谱法检测孔雀石绿与硝基呋喃类及其代谢物。结果孔雀石绿及其代谢物检出率和硝基呋喃类代谢物检出率分别为33%和14%；孔雀石绿残留主要是隐色孔雀石绿,硝基呋喃类残留主要为氨基脲和3-氨基-2-恶唑烷酮；中山鳜鱼中孔雀石绿和氨基脲检出率最高,分别为83%和50%,佛山鲩体内隐色孔雀石绿检出率为20%；批发市场鳜中孔雀石绿检出率为38%,零售市场高达71%。结论孔雀石绿及其代谢物检出率高于硝基呋喃类代谢物检出率。孔雀石绿残留主要以其代谢物隐色孔雀石绿形式存在,4种硝基呋喃药物中呋喃唑酮和呋喃西林使用更为普遍。中山和佛山是传统的水产养殖发达地区,孔雀石绿和硝基呋喃类代谢物残留水平相对其他采样点更加严重。与批发市场相比,零售市场鳜鱼孔雀石绿残留检出率更高,应当重点关注。
목적：연구광동성시수궐화혼체내공작석록(malachite green, MG)여초기부남류(nitrofurans, NFs)급기대사물잔류현상。방법111빈궐화혼양품분별구자엄주、심수、불산、중산、산두화무명등지,채용고효액상색보-천련질보법검측공작석록여초기부남류급기대사물。결과공작석록급기대사물검출솔화초기부남류대사물검출솔분별위33%화14%；공작석록잔류주요시은색공작석록,초기부남류잔류주요위안기뇨화3-안기-2-악서완동；중산궐어중공작석록화안기뇨검출솔최고,분별위83%화50%,불산혼체내은색공작석록검출솔위20%；비발시장궐중공작석록검출솔위38%,령수시장고체71%。결론공작석록급기대사물검출솔고우초기부남류대사물검출솔。공작석록잔류주요이기대사물은색공작석록형식존재,4충초기부남약물중부남서동화부남서림사용경위보편。중산화불산시전통적수산양식발체지구,공작석록화초기부남류대사물잔류수평상대기타채양점경가엄중。여비발시장상비,령수시장궐어공작석록잔류검출솔경고,응당중점관주。
Objective To determine the levels of malachite green (MG) and nitrofurans (NFs) residues inSini-perca chuatsiandCtenopharynogodon idellain Guangdong.Methods A total of 111Siniperca chuatsiandCteno-pharynogodon idella samples were collected in Guangzhou, Shenzhen, Foshan, Zhongshan, Shantou and Maoming, Guangdong province. The concentration of malachite green and nitrofurans residues were quantified by high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).Results The detection rates of MG and nitrofurans residues were 33% and 14%. MG residues were mainlyleucomalachite green (LMG), and the major nitrifurans residues weresemicarbazid (SEM) and3-amino-2-oxazolidinone (AOZ). The detection rates of MG and SEM inSiniperca chuatsi of Zhongshan were the highest, 83% and 50% respectively. The highest detection rate of LMG inCtenopharynogodon idellaappeared in Foshan, which was 20%. The detection rate of malachite green inSiniperca chuatsin retail markets was 71%, but in wholesales was 38%.ConclusionThe detection rate of MG residues was much higher than that of nitrofurans residues. MG residues in fish was mainly its metabolite LMG, and the major residues of NFs were SEM and AOZ. As the traditional aquaculture bases in Guangdong, Zhongshan and Foshan had more serious situation than other sam-pling places. The detection rate of malachite green inSiniperca chuatsof retail marketswas much higher than that in wholesales, so the management agencies should pay more attention to this situation.