CAJ | 학술논문

目的：探讨连云港农村地区高血压人群血清的 ApoB/ApoAⅠ比值的相关因素。方法采集1038例（男384例，女654例）平均年龄为（56.1±8.4）岁的连云港农村地区高血压人群为研究对象；采用DIMENSION RXL-MAX全自动生化仪测量ApoB、ApoAⅠ、尿酸等生化项目。结果连云港农村地区高血压人群的ApoB/ApoAⅠ均值水平为0.74±0.13，男性（0.76±0.14）显著高于女性（0.73±0.13）（P＜0.05）；多元线性回归显示血尿酸、BMI与ApoB/ApoAⅠ比值的升高呈正相关。结论连云港农村地区高血压人群血尿酸和 BMI 的增加均与 ApoB/ApoAⅠ比值升高显著相关。高尿酸和 BMI 的增加与 ApoB/ApoAⅠ升高具有较强的聚集效应，研究这种多重危险因素聚集的现象将为高血压人群心血管疾病的防治提供更多重要线索。
목적：탐토련운항농촌지구고혈압인군혈청적 ApoB/ApoAⅠ비치적상관인소。방법채집1038례（남384례，녀654례）평균년령위（56.1±8.4）세적련운항농촌지구고혈압인군위연구대상；채용DIMENSION RXL-MAX전자동생화의측량ApoB、ApoAⅠ、뇨산등생화항목。결과련운항농촌지구고혈압인군적ApoB/ApoAⅠ균치수평위0.74±0.13，남성（0.76±0.14）현저고우녀성（0.73±0.13）（P＜0.05）；다원선성회귀현시혈뇨산、BMI여ApoB/ApoAⅠ비치적승고정정상관。결론련운항농촌지구고혈압인군혈뇨산화 BMI 적증가균여 ApoB/ApoAⅠ비치승고현저상관。고뇨산화 BMI 적증가여 ApoB/ApoAⅠ승고구유교강적취집효응，연구저충다중위험인소취집적현상장위고혈압인군심혈관질병적방치제공경다중요선색。
ObjectiveTo investigate the associated factors of ApoB/ApoAⅠ ratio in Lianyungang hypertensive adults of rural areas.MethodsCollected 1 038 cases (384 cases of male, 654 cases of female), the average age was (56.1±8.4) years of Lianyungang hypertensive population in rural areas for the study; DIMENSIONRXL-MAX automatic biochemical analyzer was used to test the biochemical items including ApoB, ApoAⅠ and serum uric acid, and so on.ResultsAmong hypertensive patients in rural areas of Lianyungang city, the mean ApoB/ApoAⅠ ratio of total population was 0.74±0.13, male (0.76±0.14) was significantly higher than that in female (0.73±0.13),P<0.05. In multiple linear regression analysis, serum uric acid, body mass index (BMI) were positively associative with the increased ApoB/ApoAⅠ ratio.ConclusionsOur study results show that serum uric acid and BMI were positively associated with the increased ApoB/ApoAⅠ ratio in Lianyungang rural hypertensive patients. High uric acid and increased BMI and ApoB/ApoAⅠ ratio raised with a strong aggregation effect, to study this phenomenon of multiple risk factors clustering will provide more important clues for cardiovascular disease prevention and control of hypertension crowd.