CAJ | 학술논문

目的：了解老年髋部骨折愈合期男、女性骨代谢标志物的变化，建立其自身的变化特征。方法对四川省骨科医院近两年收治的老年髋部骨折患者，在骨折初、愈合期第1、2、3、4、7周时测定其β胶原特殊序列（β‐CTX）、骨钙素片段中断（N‐MID）。结果老年髋部骨折患者β‐CTX均呈增加趋势，但男性增加晚于女性，且在第7周时较之前有下降。N‐MID在第7周时均明显增加，但男性在第1周时下降，第2周开始逐渐增加，女性在第1周时即增加，而在第2周时降低，以后又逐渐增加。结论老年髋部骨折患者骨折愈合期骨代谢标志物的变化因男女性别不同而有各自的特点。
목적：료해노년관부골절유합기남、녀성골대사표지물적변화，건립기자신적변화특정。방법대사천성골과의원근량년수치적노년관부골절환자，재골절초、유합기제1、2、3、4、7주시측정기β효원특수서렬（β‐CTX）、골개소편단중단（N‐MID）。결과노년관부골절환자β‐CTX균정증가추세，단남성증가만우녀성，차재제7주시교지전유하강。N‐MID재제7주시균명현증가，단남성재제1주시하강，제2주개시축점증가，녀성재제1주시즉증가，이재제2주시강저，이후우축점증가。결론노년관부골절환자골절유합기골대사표지물적변화인남녀성별불동이유각자적특점。
Objective To understand the changes of bone metabolism markers in men and women during heal‐ing period of elderly hip fracture for establishing their own change characteristics .Methods β‐CTX and N‐MID were detected at the early fracture ,1 ,2 ,3 ,4 ,7 weeks of fracture healing in the elderly patients with hip fractures admitted in our hospital in the last two years .Results β‐CTX showed a increasing trend in elderly patients with hip fracture , but the increase in males was later than that in females ,and which at 7 weeks was decreased than before .N‐MID at 7 weeks was significantly increased ,which in the males was decreased at 1 week and gradually increased at 2 weeks , while which in females was increased at 1 week and decreased at 2 weeks ,but later gradually increased .Conclusion The changes of bone metabolism markers in the elderly patients with hip fracture have their own characteristics dur‐ing the fracture healing period due to different genders .