CAJ | 학술논문

目的：探讨百特泵持续静脉输注5-Fu联合化疗的近期疗效、不良反应和护理效果。方法将我院肿瘤科2011年3月至2013年11月接受百特泵持续静脉输注5-Fu和间歇静脉输注5-Fu两种联合化疗的病人分为治疗组和对照组，对比研究两组患者的满意度、疗效、体质状况、药物毒副反应间的差异。结果治疗组患者满意度、体质状况改善以及消化道反应和周围静脉炎的副作用较对照组减低，并有统计学意义(P<0.05)；而在疗效、骨髓抑制和神经毒性方面无统计学差异(P>0.05)。结论百特泵持续静脉输注5-Fu联合化疗近期疗效满意，患者耐受性好，毒副反应减轻，化疗过程中须加强综合护理措施。
목적：탐토백특빙지속정맥수주5-Fu연합화료적근기료효、불량반응화호리효과。방법장아원종류과2011년3월지2013년11월접수백특빙지속정맥수주5-Fu화간헐정맥수주5-Fu량충연합화료적병인분위치료조화대조조，대비연구량조환자적만의도、료효、체질상황、약물독부반응간적차이。결과치료조환자만의도、체질상황개선이급소화도반응화주위정맥염적부작용교대조조감저，병유통계학의의(P<0.05)；이재료효、골수억제화신경독성방면무통계학차이(P>0.05)。결론백특빙지속정맥수주5-Fu연합화료근기료효만의，환자내수성호，독부반응감경，화료과정중수가강종합호리조시。
Objective To evaluate term efficacy, adverse reactions and nursing effect of intravenous continuous infusion of 5-Fu with Baxter pump combined with chemotherapy. Methods Patients with continuous infusion of 5-Fu in our hospital were selected as observation group, and patients with intermittent infusion were selected as control group. Curative effect, satisfaction, physical condition and adverse reactions were compared between two groups. Results There were statistical differences in satisfaction, physical condition, gastrointestinal side effects and phlebitis between two groups (P <0.05). However, there were no statistical differences in therapeutic effect, bone marrow depression and neurotoxicity (P>0.05). Conclusions Continuous intravenous infusion of 5-Fu with Baxter pump is effective for patients with combined chemotherapy, with fewer adverse reactions. Comprehensive nursing mesausres should be strenthened during chemotherapy.