CAJ | 학술논문

目的：探讨特应性斑贴试验用于特应性皮炎过敏原检测(APT)的临床意义。方法选取2010年5月至2012年7月间于我院皮肤科门诊诊治的特应性皮炎患者92例，采用特应性斑贴试验进行过敏原检测，对比分析其与杂孕栽、泽陨早耘检测的临床效果。结果在选取的5种常见吸入性过敏原中，户尘螨和粉尘螨的阳性检出率最高(分别为25.00豫、29.35豫)，均低于杂孕栽和泽I早耘检测，但对于食入性过敏原A孕栽阳性率较其他两种检测方法的阳性率显著升高；对于吸入性过敏原A孕栽检测的特异性均较高，但敏感度较低；而杂孕栽诊断结果显示，除蟑螂外其特异度均达到90豫以上，且敏感度也较高。结论对于吸入性过敏原，A孕栽诊断具有较高的特异度，但敏感性较差；但对于食入性过敏原的检测上，A孕栽具有更好的临床效果。
목적：탐토특응성반첩시험용우특응성피염과민원검측(APT)적림상의의。방법선취2010년5월지2012년7월간우아원피부과문진진치적특응성피염환자92례，채용특응성반첩시험진행과민원검측，대비분석기여잡잉재、택운조운검측적림상효과。결과재선취적5충상견흡입성과민원중，호진만화분진만적양성검출솔최고(분별위25.00예、29.35예)，균저우잡잉재화택I조운검측，단대우식입성과민원A잉재양성솔교기타량충검측방법적양성솔현저승고；대우흡입성과민원A잉재검측적특이성균교고，단민감도교저；이잡잉재진단결과현시，제장랑외기특이도균체도90예이상，차민감도야교고。결론대우흡입성과민원，A잉재진단구유교고적특이도，단민감성교차；단대우식입성과민원적검측상，A잉재구유경호적림상효과。
Objective To explore the clinical significance of atopy patch test (APT) in the detection of allergens of atopic dermatitis (AD). Methods 92 patients with atopic dermatitis treated in our hospital from May 2010 to July 2012 were selected. All cases received allergen detection by atopy patch test. The detection results were compared with the results of SPT and sIgE. Results The positive rate of dermatophagoides pteronyssinus and dermatophagoides farinae of APT was 25.00%and 29.35%respectively, lower than the results of SPT and sIgE detection. The positive rate of ingestive allergen of APT was higher than that of SPT and sIgE. For inhalational allergen, APT had high specificity but low sensitivity; the specificity of SPT was over 90% in addition to the cockroach, and SPT had high sensitivity. Conclusions For inhalational allergen, APT has high specificity but low sensitivity;for ingestive allergen, APT has better detection effect.