CAJ | 학술논문

目的：探讨普瑞巴林对带状疱疹后遗神经痛的有效性与安全性。方法选择带状疱疹后遗神经痛患者72例并随机分为两组各36例。观察组采用普瑞巴林治疗，对照组采用加巴喷丁治疗，观察比较两组的疗效及不良反应。结果治疗4周后，观察组总有效率为83.33豫，显著高于对照组(孕<0.05)；两组的灾A杂评分均比治疗前降低，但观察组降低更显著(孕<0.01)；两组均无严重不良反应发生。结论普瑞巴林治疗带状疱疹后遗神经痛安全有效，能显著改善患者的灾A杂评分，无严重不良反应。
목적：탐토보서파림대대상포진후유신경통적유효성여안전성。방법선택대상포진후유신경통환자72례병수궤분위량조각36례。관찰조채용보서파림치료，대조조채용가파분정치료，관찰비교량조적료효급불량반응。결과치료4주후，관찰조총유효솔위83.33예，현저고우대조조(잉<0.05)；량조적재A잡평분균비치료전강저，단관찰조강저경현저(잉<0.01)；량조균무엄중불량반응발생。결론보서파림치료대상포진후유신경통안전유효，능현저개선환자적재A잡평분，무엄중불량반응。
Objective To explore the effectiveness and safety of pregabalin in the treatment of post-herpetic neuralgia. Methods 72 patients with post-herpetic neuralgia were randomly divided into two groups, with 36 cases in each group. Patients in the observation group were treated with Pregabalin, while patients in the control group were treated with gabapentin. The curative effect and adverse reactions were observed and compared between two groups. Results After 4 weeks of treatment, the total effective rate of observation group was 83.33%, significantly higher than 61.11%of control group (P<0.05). Both groups had decreased VAS score after treatment, but the observation group had more significant decrease (P <0.01). No severe reaction was found in both groups. Conclusions Pregabalin in the treatment of post-herpetic neuralgia is effective and safe, which can significantly improve patients' VAS score and has no serve adverse reactions.