中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2013年
4期
247-249
,共3页
青光眼,难治性%角膜内皮细胞%眼外科手术%眼压
青光眼,難治性%角膜內皮細胞%眼外科手術%眼壓
청광안,난치성%각막내피세포%안외과수술%안압
Glaucoma,refractory%Corneal endothelium cells%Ophthalmologic surgical procedure%Intraocular pressure
目的 观察Ahmed阀植入术对角膜内皮细胞的影响.方法 回顾性病例研究.对21例(21眼)难治性青光眼行Ahmed阀植入术.术眼于术前ld和术后1周、1个月、3个月、6个月、12个月,对侧眼于术前ld和术后12个月行角膜内皮镜检查,记录角膜内皮细胞密度,计算角膜内皮细胞丢失率;测量眼压、前房深度,观察引流管位置.角膜内皮细胞密度值比较采用方差分析.结果 行Ahmed阀植入术的21眼术后角膜内皮细胞密度均下降,随着时间的推移,角膜内皮细胞丢失逐步增多,术后1周、1个月、3个月、6个月和12个月内皮细胞密度分别为(2299 ±234)个/mm2、(2062 ±234)个/mm2、(2015 ±223)个/mm2、(1999±222)个/mm2和(1901 ±210)个/mm2,与术前的(2306 ±229)个/mm2比较,差异有统计学意义(F=15.3,P＜0.01).术后各时间点角膜内皮细胞丢失率分别为0.3％、10.5％、12.6％、13.2％、17.5％.结论 Ahmed阀植入术后,角膜内皮细胞短期内存在丢失现象.
目的 觀察Ahmed閥植入術對角膜內皮細胞的影響.方法 迴顧性病例研究.對21例(21眼)難治性青光眼行Ahmed閥植入術.術眼于術前ld和術後1週、1箇月、3箇月、6箇月、12箇月,對側眼于術前ld和術後12箇月行角膜內皮鏡檢查,記錄角膜內皮細胞密度,計算角膜內皮細胞丟失率;測量眼壓、前房深度,觀察引流管位置.角膜內皮細胞密度值比較採用方差分析.結果 行Ahmed閥植入術的21眼術後角膜內皮細胞密度均下降,隨著時間的推移,角膜內皮細胞丟失逐步增多,術後1週、1箇月、3箇月、6箇月和12箇月內皮細胞密度分彆為(2299 ±234)箇/mm2、(2062 ±234)箇/mm2、(2015 ±223)箇/mm2、(1999±222)箇/mm2和(1901 ±210)箇/mm2,與術前的(2306 ±229)箇/mm2比較,差異有統計學意義(F=15.3,P＜0.01).術後各時間點角膜內皮細胞丟失率分彆為0.3％、10.5％、12.6％、13.2％、17.5％.結論 Ahmed閥植入術後,角膜內皮細胞短期內存在丟失現象.
목적 관찰Ahmed벌식입술대각막내피세포적영향.방법 회고성병례연구.대21례(21안)난치성청광안행Ahmed벌식입술.술안우술전ld화술후1주、1개월、3개월、6개월、12개월,대측안우술전ld화술후12개월행각막내피경검사,기록각막내피세포밀도,계산각막내피세포주실솔;측량안압、전방심도,관찰인류관위치.각막내피세포밀도치비교채용방차분석.결과 행Ahmed벌식입술적21안술후각막내피세포밀도균하강,수착시간적추이,각막내피세포주실축보증다,술후1주、1개월、3개월、6개월화12개월내피세포밀도분별위(2299 ±234)개/mm2、(2062 ±234)개/mm2、(2015 ±223)개/mm2、(1999±222)개/mm2화(1901 ±210)개/mm2,여술전적(2306 ±229)개/mm2비교,차이유통계학의의(F=15.3,P＜0.01).술후각시간점각막내피세포주실솔분별위0.3％、10.5％、12.6％、13.2％、17.5％.결론 Ahmed벌식입술후,각막내피세포단기내존재주실현상.
Objective To evaluate the influence of Ahmed glaucoma valve implantation on the corneal endothelium during a one-year follow-up period.Methods In a retrospective case study,21 patients (21 eyes) with refractory glaucoma underwent Ahmed glaucoma valve implantation.The corneal endothelium was assessed by spectral microscopy 1 day preoperatively and 1 week and 1,3,6 and 12 months postoperatively.Density and loss ratio of the corneal endothelium cells were assessed and calculated.Intraocular pressure (IOP),anterior chamber depth (AC) and the position of the drainage tube were also observed.An analysis of variance (ANOVA) was used to compare corneal endothelial cell density at the different time points.Results The density of corneal endothelium cells decreased after Ahmed glaucoma valve implantation in all 21 eyes.The loss ratio of the corneal endothelium increased over time.Compared to a preoperative value of 2306±229 cells/mm2,the corneal endothelium at 1 week postoperatively was 2299±234 cells/mm2,at 1 month was 2062 ±234 cells/mm2,at 3 months was 2015±223 cells/mm2,at 6 months was 1999 ±222 cells/mm2,and at 12 months was 1901±210 cells/mm2 (F=15.3,P＜0.01).The loss ratio of the corneal endothelium were 0.3％,10.5％,12.6％,13.2％,17.5％.Conclusion There is a loss in corneal endothelium during the short time period after Ahmed glaucoma valve implantation.
