国际医学放射学杂志
國際醫學放射學雜誌
국제의학방사학잡지
INTERNATIONAL JOURNAL OF MEDICAL RADIOLOGY
2014年
6期
548-551
,共4页
原发性胆汁性肝硬化%磁共振成像%对比增强%功能成像
原髮性膽汁性肝硬化%磁共振成像%對比增彊%功能成像
원발성담즙성간경화%자공진성상%대비증강%공능성상
Primary biliary cirrhosis%Magnetic resonance imaging%Contrast-enhancement%Functional imaging
原发性胆汁性肝硬化（PBC）是一种慢性肝内胆汁淤积性自身免疫性疾病，近年来由于认识的不断提高以及检测技术的进步，检出率大为增加。早期应用熊去氧胆酸（UDCA）治疗可以延缓疾病的进展，提高生存质量，终末期病人失去对UDCA的有效反应，重症病人需行肝移植治疗。因此早期发现和确诊PBC，对制定治疗方案、监测病变程度和病情发展、判断预后等均有重要作用。就常规MRI、功能MRI以及增强MRI在PBC诊断中的研究现状和进展予以综述。
原髮性膽汁性肝硬化（PBC）是一種慢性肝內膽汁淤積性自身免疫性疾病，近年來由于認識的不斷提高以及檢測技術的進步，檢齣率大為增加。早期應用熊去氧膽痠（UDCA）治療可以延緩疾病的進展，提高生存質量，終末期病人失去對UDCA的有效反應，重癥病人需行肝移植治療。因此早期髮現和確診PBC，對製定治療方案、鑑測病變程度和病情髮展、判斷預後等均有重要作用。就常規MRI、功能MRI以及增彊MRI在PBC診斷中的研究現狀和進展予以綜述。
원발성담즙성간경화（PBC）시일충만성간내담즙어적성자신면역성질병，근년래유우인식적불단제고이급검측기술적진보，검출솔대위증가。조기응용웅거양담산（UDCA）치료가이연완질병적진전，제고생존질량，종말기병인실거대UDCA적유효반응，중증병인수행간이식치료。인차조기발현화학진PBC，대제정치료방안、감측병변정도화병정발전、판단예후등균유중요작용。취상규MRI、공능MRI이급증강MRI재PBC진단중적연구현상화진전여이종술。
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease which is considered to be an autoimmune disorder. In recent years, the detection rate of PBC shows a rising trend due to the improvement of understanding and the progress of technology. Currently, early application of ursodeoxycholic acid (UDCA) therapy can delay the progress of the disease. However, end-stage patients lose effective response to UDCA and critically ill patients require liver transplantation, so early detection and diagnosis of PBC are important in planning treatment, monitoring the severity and progression of the disease and assessing prognosis, etc. In this paper, the research status and progress of MRI in the diagnosis of PBC were reviewed.
