CAJ | 학술논문

肝纤维化是各种慢性肝病向肝硬化发展的必经过程，该过程是潜隐渐进的，且肝纤维化早期阶段是可逆的。早期定量诊断肝纤维化对其治疗效果、预后评估及促进其逆转具有重要意义。随着功能MRI技术，特别是MR扩散加权成像及扩散张量成像技术的发展，肝纤维化的无创性定量诊断取得一定进展。着重就MR扩散张量成像对肝纤维化的定量诊断与分期研究进展予以综述。
간섬유화시각충만성간병향간경화발전적필경과정，해과정시잠은점진적，차간섬유화조기계단시가역적。조기정량진단간섬유화대기치료효과、예후평고급촉진기역전구유중요의의。수착공능MRI기술，특별시MR확산가권성상급확산장량성상기술적발전，간섬유화적무창성정량진단취득일정진전。착중취MR확산장량성상대간섬유화적정량진단여분기연구진전여이종술。
Liver fibrosis is the common process of liver cirrhosis in various chronic liver diseases . This process is latent and gradual, and is reversible in the early-stage . Early quantitative diagnosis of liver fibrosis is of great significance for the evaluation of treatment response and prognosis, and the promotion of inversion.With the development of functional magnetic resonance imaging, especially the diffusion weighted imaging and diffusion tensor imaging, noninvasive quantitative diagnosis of liver fibrosis has progressed greatly. We reviewed the progress in quantitatively diagnosing and staging liver fibrosis with diffusion tensor imaging.