CAJ | 학술논문

原发全面性癫日病人大脑无器质性病变，常规MRI检查无法发现异常。目前普遍认为病人皮质-丘脑网络存在微细结构及功能上的异常改变，这种异常改变在原发全面性癫日的发病中起着重要作用。多模态影像技术联合应用可从结构、功能、血流及代谢等方面观测皮质-丘脑异常，为研究原发全面性癫日的病理生理学机制提供方法。就原发全面性癫日皮质-丘脑网络的神经放射学研究进展进行综述。
원발전면성전일병인대뇌무기질성병변，상규MRI검사무법발현이상。목전보편인위병인피질-구뇌망락존재미세결구급공능상적이상개변，저충이상개변재원발전면성전일적발병중기착중요작용。다모태영상기술연합응용가종결구、공능、혈류급대사등방면관측피질-구뇌이상，위연구원발전면성전일적병리생이학궤제제공방법。취원발전면성전일피질-구뇌망락적신경방사학연구진전진행종술。
Patients with idiopathic generalized epilepsy present no abnormalities in routine MRI. It is currently proposed that abnormal structural and functional changes in corticothalamic network play important roles in the pathogenesis of idiopathic generalized epilepsy. Multi-modality neuroimaging can provide information of structure, cerebral blood flow and metabolism of human brain, and can be used to investigate the mechanism of idiopathic generalized epilepsy. The research progresses of corticothalamic network in neuroimaging were reviewed in this article.