CAJ | 학술논문

目的：了解广东省潮州市2013年度流行性感冒流行特征及病毒流行株构成。方法采集监测哨点医院疑似流感样患者咽拭子标本，采用实时荧光 PCR（real-time RT-PCR）检测病毒核酸。结果全市流感检测哨点医院共采集标本830份，流感病毒核酸阳性为53份，阳性率为6.39％；其中新甲型 H1N1流感占49.06％（26／53）、乙型流感病毒占28.30％（15／53）、季节性流感病毒 H3亚型占22.64％（12／53），未分离到季节性流感病毒H1。4月和12月为年度病毒检测高峰。病毒感染率以5～14岁组（14.12％）最高，与其它组比较存在统计学差异（P <0.05）。结论2013年度潮州市流感病毒优势株为新型甲型H1N1，全年有2个流行高峰，在4月和12月，主要发病人群为学龄前儿童和小学生。
목적：료해광동성조주시2013년도류행성감모류행특정급병독류행주구성。방법채집감측초점의원의사류감양환자인식자표본，채용실시형광 PCR（real-time RT-PCR）검측병독핵산。결과전시류감검측초점의원공채집표본830빈，류감병독핵산양성위53빈，양성솔위6.39％；기중신갑형 H1N1류감점49.06％（26／53）、을형류감병독점28.30％（15／53）、계절성류감병독 H3아형점22.64％（12／53），미분리도계절성류감병독H1。4월화12월위년도병독검측고봉。병독감염솔이5～14세조（14.12％）최고，여기타조비교존재통계학차이（P <0.05）。결론2013년도조주시류감병독우세주위신형갑형H1N1，전년유2개류행고봉，재4월화12월，주요발병인군위학령전인동화소학생。
Objective To analyze the epidemiological characteristics of influenza and the composition of epidemic strains in Chaozhou, Guangdong province, 2013. Methods Throat swabs were collected from influenza-like patients in influenza-monitoring hospitals and real-time RT-PCR was used to detect influenza viruses in these samples. Results 53 strains of influenza viruses were detected from the 830 throat swabs (6.39%), including 26 strains of novel influenza A (H1N1) viruses (49.06%, 26/53), 15 strains of B influenza virus (28.30%, 15/53) and 12 strains of H3 subtype influenza virus (22.64%, 12/53). None of H1 subtype influenza virus was isolated from these samples. The annual peaks of virus detection were in April and December. The highest virus prevalence (14.12%) was observed in 5 ~ 14 years old group and statistical difference was found between it and other groups (P < 0.05). Conclusion The predominant influenza virus detected in Chaozhou in 2013 was H1N1 virus. Two prevalent peaks of influenza viruses were in April and December and the infections mainly occurred among pre-school children and pupils.