CAJ | 학술논문

目的：探讨磁共振扩散加权成像(DWI)及表观扩散系数(ADC)与直肠管状腺癌病理分化程度的相关性。方法回顾性分析在本院术前行 MRI 检查且手术病理证实的38例直肠管状腺癌患者的 DWI 影像特点,其中高分化9例、中分化15例、低分化14例。在 b 值为0 s/mm2和1000 s/mm2条件下计算 ADC 值并分析其与肿瘤分化程度的相关性。结果高分化组平均 ADC值(0.92±0.05)×10-3 mm2/s；中分化组平均 ADC 值(0.79±0.10)×10-3 mm2/s；低分化组平均 ADC 值(0.71±0.06)×10-3 mm2/s。不同分化程度的直肠管状腺癌各组别 ADC 值有明显差异(P <0.05)；ADC 值与肿瘤分化恶性程度呈负相关,相关系数为-0.704,P <0.01。结论DWI 及 ADC 值的测量可成为一种判断直肠管状腺癌分化恶性程度的重要检查手段。
목적：탐토자공진확산가권성상(DWI)급표관확산계수(ADC)여직장관상선암병리분화정도적상관성。방법회고성분석재본원술전행 MRI 검사차수술병리증실적38례직장관상선암환자적 DWI 영상특점,기중고분화9례、중분화15례、저분화14례。재 b 치위0 s/mm2화1000 s/mm2조건하계산 ADC 치병분석기여종류분화정도적상관성。결과고분화조평균 ADC치(0.92±0.05)×10-3 mm2/s；중분화조평균 ADC 치(0.79±0.10)×10-3 mm2/s；저분화조평균 ADC 치(0.71±0.06)×10-3 mm2/s。불동분화정도적직장관상선암각조별 ADC 치유명현차이(P <0.05)；ADC 치여종류분화악성정도정부상관,상관계수위-0.704,P <0.01。결론DWI 급 ADC 치적측량가성위일충판단직장관상선암분화악성정도적중요검사수단。
Objective To investigate the diffusion-weighted imaging (DWI)characteristics and the correlation of diffusion coeffi-cient (ADC)and differentiation grade of rectal tubular adenocarcinoma.Methods The DWI characteristics of thirty-eight patients pathologically comfirmed rectal tubular adenocarcinomas were evaluated respectively.There were 9 highly differentiated tubular ade-nocarcinomas,1 5 moderately differentiated tubular adenocarcinomas and 14 poorly differentiated tubular adenocarcinomas.The ADC value was calculated from two different factors (0 and 1 000 s/mm2 ).The correlation between ADC value and the differentiated de-gree of tumour was statistically analysed.Results The mean ADC for highly differentiated group was (0.92±0.05)×10 -3 mm2/s, and the mean ADC for moderately differentiated group was (0.79 ± 0.10)× 10 -3 mm2/s whereas that for poorly differentiated group was (0.71±0.06)×10 -3 mm2/s.The difference among three groups was statistically significant(P <0.05).The ADC value and the differentiated degree of tumour were negatively correlated(Spearman r =-0.704)P<0.01.Conclusion DWI and ADC value can be a useful estimating for the differentiation of rectal tubular adenocarcinoma.