CAJ | 학술논문

目的：探讨背景信号抑制扩散加权成像(DWIBS)在直肠癌淋巴结转移诊断中的应用价值。方法30例经肠镜确诊的直肠癌患者行常规 MRI 及 DWIBS 检查。对照术后病理结果,确定转移性和非转移性淋巴结。测量淋巴结实质部分的表观扩散系数(ADC)值,比较差异有无统计学意义,采用受试者工作特征曲线(ROC)分析确定 ADC 值的诊断阈值。结果73枚淋巴结中,转移性淋巴结52枚,非转移性淋巴结21枚。转移性与非转移性淋巴结实质部分的 ADC 值分别为(0.881±0.094)×10-3 mm2/s和(1.072±0.108)×10-3 mm2/s,差异有统计学意义(P <0.05)。当以 ADC=0.957×10-3 mm2/s 作为鉴别转移性与非转移性淋巴结的诊断指标,其诊断价值为优(Az 值=0.919,P <0.05),灵敏度为90.5%,特异度为80.8%。结论ADC 值可用于直肠癌淋巴结转移的鉴别,DWIBS 在直肠癌淋巴结转移的评估中具有较高的应用价值。
목적：탐토배경신호억제확산가권성상(DWIBS)재직장암림파결전이진단중적응용개치。방법30례경장경학진적직장암환자행상규 MRI 급 DWIBS 검사。대조술후병리결과,학정전이성화비전이성림파결。측량림파결실질부분적표관확산계수(ADC)치,비교차이유무통계학의의,채용수시자공작특정곡선(ROC)분석학정 ADC 치적진단역치。결과73매림파결중,전이성림파결52매,비전이성림파결21매。전이성여비전이성림파결실질부분적 ADC 치분별위(0.881±0.094)×10-3 mm2/s화(1.072±0.108)×10-3 mm2/s,차이유통계학의의(P <0.05)。당이 ADC=0.957×10-3 mm2/s 작위감별전이성여비전이성림파결적진단지표,기진단개치위우(Az 치=0.919,P <0.05),령민도위90.5%,특이도위80.8%。결론ADC 치가용우직장암림파결전이적감별,DWIBS 재직장암림파결전이적평고중구유교고적응용개치。
Objective To investigate the application value of diffusion-weighted imaging with background suppression (DWIBS) in lymph node metastasis of rectal cancer.Methods 30 patients with rectal cancer diagnosed by colonoscopy underwent routine MRI and DWIBS examinations.Metastatic and non-metastatic lymph nodes were confirmed by postoperative pathology.Apparent diffu-sion coefficient (ADC)values of the solid part of metastatic and non-metastatic lymph nodes were measured and compared.ROC curve analysis was used to define the threshold between the metastatic and non-metastatic lymph nodes.Results In all 73 lymph nodes,there were 52 metastatic lymph nodes and the other 21 were non-metastatic.ADC values of the solid part of metastatic and non-metastatic lymph nodes were (0.881 ± 0.094)× 10 -3 mm2/s and (1.072 ± 0.108)×10 -3 mm2/s respectively,the difference was statistically significant (P <0.05).With the threshold ADC value of 0.957×10 -3 mm2/s,the sensitivity and specificity for dif-ferentiating metastatic from non-metastatic lymph nodes were 90.5% and 80.8% respectively.The diagnostic value was excellent (Az value = 0.91 9,P <0.05).Conclusion ADC values may be used to differentiate lymph node metastasis of rectal cancer,and DWIBS has higher application value in assessing lymph node metastasis of rectal cancer.