CAJ | 학술논문

目的：评估乳腺疾病患者中钆对比剂对 MRI 扩散加权成像(DWI)和病变的表观扩散系数(ADC)是否有显著性影响，分析增强前后 ADC 值在乳腺良恶性病变鉴别中的价值。方法收集本院行乳腺 MRI 检查的35例患者共计38个病灶，所有病灶均经病理证实。笔者对比了增强前后正常乳腺组织及病灶的信噪比(SNR)和对比噪声比(CNR)，以及病灶增强前后的 ADC 值。结果(1)增强前后 DWI 的 SNR 及 CNR 无统计学差异；(2)恶性病灶增强前后的 ADC 值存在统计学差异，增强前后 ADC 值平均降幅11.6%；良性病灶增强前后的 ADC 值无统计学差异。结论增强后 ADC 值能够更好地反映乳腺病变的恶性潜能。
목적：평고유선질병환자중구대비제대 MRI 확산가권성상(DWI)화병변적표관확산계수(ADC)시부유현저성영향，분석증강전후 ADC 치재유선량악성병변감별중적개치。방법수집본원행유선 MRI 검사적35례환자공계38개병조，소유병조균경병리증실。필자대비료증강전후정상유선조직급병조적신조비(SNR)화대비조성비(CNR)，이급병조증강전후적 ADC 치。결과(1)증강전후 DWI 적 SNR 급 CNR 무통계학차이；(2)악성병조증강전후적 ADC 치존재통계학차이，증강전후 ADC 치평균강폭11.6%；량성병조증강전후적 ADC 치무통계학차이。결론증강후 ADC 치능구경호지반영유선병변적악성잠능。
Objective To evaluate the effect of intravenous administration of gadolinium-DTPA on diffusion weighted imaging (DWI)of breast lesions and apparent diffusion coefficient(ADC)values,and to evaluate the diagnostic performance of post-contrast ADC for differentiating benign from malignant lesions in breast.Methods Thirty-eight histopathologically-confirmed breast lesions were analyzed.We examined the signal to noise ratio(SNR)of normal breast tissue and lesions and evaluated the contrast to noise ratio(CNR)of each lesion.We also assessed the relation between pre-and post-contrast ADC values.Results SNRs and CNRs of DWI before and after contrast were not significantly different.The mean post-contrast ADC values for malignant lesions significantly decreased after contrast injected (mean of -1 1.6%),while ADC values in the benign lesions were not significantly different before and after contrast.Conclusion Post-contrast ADC values may be a better indicator of potential breast tumors than pre-contrast ADC values.