CAJ | 학술논문

目的：探讨自拟雄黄复方治疗反应性关节炎的临床疗效，并初步评估其安全性。方法：选取反应性关节炎患者68例，随机分为治疗组39例和对照组29例。治疗组给予自拟雄黄复方治疗，对照组给予双氯芬酸钠缓释片+柳氮磺吡啶+甲氨蝶呤治疗，两组6个月后进行疗效评定。结果：治疗组临床治愈30例，显效5例，有效3例，有效率97.44%；对照组临床治愈16例，显效7例，有效3例，无效3例，有效率89.66%。两组比较，差异有统计学意义（P<0.05）。两组治疗后临床指标改善比较，差异无统计学意义（P>0.05）；两组不良反应比较，差异无统计学意义（P>0.05）。结论：雄黄复方治疗反应性关节炎具有一定疗效，且毒副作用较少。
목적：탐토자의웅황복방치료반응성관절염적림상료효，병초보평고기안전성。방법：선취반응성관절염환자68례，수궤분위치료조39례화대조조29례。치료조급여자의웅황복방치료，대조조급여쌍록분산납완석편+류담광필정+갑안접령치료，량조6개월후진행료효평정。결과：치료조림상치유30례，현효5례，유효3례，유효솔97.44%；대조조림상치유16례，현효7례，유효3례，무효3례，유효솔89.66%。량조비교，차이유통계학의의（P<0.05）。량조치료후림상지표개선비교，차이무통계학의의（P>0.05）；량조불량반응비교，차이무통계학의의（P>0.05）。결론：웅황복방치료반응성관절염구유일정료효，차독부작용교소。
Objective:To investigate the clinical efficacy of self-designed compound recipe of realgar in the treatment of reactive arthritis.Methods:68 cases with reactive arthritis were randomly divided into a treatment group (39 cases) and a control group (29 cases).The treatment group was treated with compound recipe of realgar,while the control group was given diclofenac sodium sustained release tablets plus sulfasalazine and methotrexate.After 6 months,clinical effects of he tao groups were evaluated.Results:Among the treatment group,30 cases were cured,5 cases were markedly effective and 3 cases were effective,efifciency accounting for 97.44%;while in the control group,16 cases were cured,7 cases were markedly effective,3 cases were effective,and 3 cases were invalid,efifciency accounting for 89.66%.The difference between the two groups was statistically signiifcant(P<0.05).Comparing the improvement of clinical indexes of the two groups after treatment,there was no signiifcant difference(P>0.05).The difference between adverse reactions of the two groups was not signiifcant(P>0.05).Conclusion:Compound recipe of realgar has certain curative effects in the treatment of reactive arthritis and less toxicity and side effects.