CAJ | 학술논문

目的：分析临床分离的肺炎克雷伯菌的分布特点和耐药性状况。方法从临床各科室送检标本中分离出肺炎克雷伯菌，并进行药敏试验，对结果进行分析。结果共分离获得肺炎克雷伯菌415株，分离菌主要分布在神经外科（36．1％）、呼吸内科（27．7％）和重症医学科（16．9％），74．7％来自痰标本。30．0％的分离株为产超广谱β‐内酰胺酶（ESBLs）菌株。肺炎克雷伯菌对美罗培南和亚胺培南的耐药率较低，均为0．5％。结论监测肺炎克雷伯菌的耐药趋势对指导临床用药有重要意义。
목적：분석림상분리적폐염극뢰백균적분포특점화내약성상황。방법종림상각과실송검표본중분리출폐염극뢰백균，병진행약민시험，대결과진행분석。결과공분리획득폐염극뢰백균415주，분리균주요분포재신경외과（36．1％）、호흡내과（27．7％）화중증의학과（16．9％），74．7％래자담표본。30．0％적분리주위산초엄보β‐내선알매（ESBLs）균주。폐염극뢰백균대미라배남화아알배남적내약솔교저，균위0．5％。결론감측폐염극뢰백균적내약추세대지도림상용약유중요의의。
Objective To analyze the distribution and drug resistance of the isolated strains of K lebsiella pneumonia .Methods The strains of K lebsiella pneumonia were isolated from specimens from clinical departments ,and the drug resistance was tested . The results were analyzed .Results There were 415 strains of K lebsiella pneumonia were isolated .The isolated strains distributed mainly in Department of Neurosurgery (36 .1% ) ,Department of Respiratory Medicine (27 .7% ) ,and ICU (16 .9% ) .74 .7% of the strains were isolated from sputum specimens .30 .0% of the isolated strains were ESBLs positive .The drug resistance rates of K leb‐siella pneumonia to meropenem and imipenem were both low to 0 .5% .Conclusion Monitoring the drug resistance of K lebsiella pneumonia is very important to guide the treatment .