CAJ | 학술논문

目的：探讨妊娠早期和中期甲状腺功能测定的意义。方法采用电化学发光免疫分析法对孕早期（T1组）、孕中期（T2组）和未孕妇女（对照组）进行促甲状腺素（TSH）、游离三碘甲状腺原氨酸（FT3）及游离甲状腺素（FT4）水平检测，并对结果进行分析。结果T1组FT3、FT4、TSH水平与对照组差异均有统计学意义（P＜0．05）。孕妇的甲状腺疾病总患病率为28．85％，显著高于对照组（15．00％），差异有统计学意义（P＜0．05）。甲状腺功能异常的孕妇以甲状腺功能减低和亚临床甲状腺功能减低为主。结论妊娠早期和中期进行甲状腺功能检测有利于优生优育。
목적：탐토임신조기화중기갑상선공능측정적의의。방법채용전화학발광면역분석법대잉조기（T1조）、잉중기（T2조）화미잉부녀（대조조）진행촉갑상선소（TSH）、유리삼전갑상선원안산（FT3）급유리갑상선소（FT4）수평검측，병대결과진행분석。결과T1조FT3、FT4、TSH수평여대조조차이균유통계학의의（P＜0．05）。잉부적갑상선질병총환병솔위28．85％，현저고우대조조（15．00％），차이유통계학의의（P＜0．05）。갑상선공능이상적잉부이갑상선공능감저화아림상갑상선공능감저위주。결론임신조기화중기진행갑상선공능검측유리우우생우육。
Objective To explore the significance of thyroid function determination at the first and second trimesters of pregnan‐cy .Methods Electrochemiluminescence immunoassay was used to detect the levels of TSH ,FT3 and FT4 in first trimester women (T1 group) ,second trimester women (T2 group) and non‐pregnant women (control group) ,respectively .And the results were an‐alyzed .Results There were significant difference in the levels of TSH ,FT3 and FT4 between T1 group and control group (P<0 .05) .The total prevalence rate of thyroid diseases in pregnant women was 28 .85% ,which was significantly higher than that in control group(15 .00% ) ,P<0 .05 .Hypothyroidism and subclinical hypothyroidism were the main forms of thyroid dysfunction in pregnant women .Conclusion The determination of thyroid function at the first and second trimesters of pregnancy will benefit pre‐natal and post‐natal care .