CAJ | 학술논문

目的：了解2011～2012年四川省临床分离的尿培养病原菌的分布与耐药状况。方法收集四川省细菌耐药监测网成员单位的临床尿培养病原菌分布和药敏试验数据，进行统计及分析。结果全省54家医院参加了监测，从尿液标本中总共分离出12420株病原菌，检出率排在前5位的依次是大肠埃希菌（46．5％）、屎肠球菌（7．0％）、肺炎克雷伯菌（5．8％）、粪肠球菌（5．7％）、铜绿假单胞菌（3．7％）。大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌对亚胺培南的耐药率分别为16．0％、16．7％、15．2％；对左氧氟沙星的耐药率分别为55．2％、28．2％、27．7％。屎肠球菌和粪肠球菌对万古霉素的耐药率分别为4．1％和1．4％。结论尿路感染主要病原菌仍以大肠埃希菌和肠球菌为主，临床应根据药敏试验结果选用抗菌药物。
목적：료해2011～2012년사천성림상분리적뇨배양병원균적분포여내약상황。방법수집사천성세균내약감측망성원단위적림상뇨배양병원균분포화약민시험수거，진행통계급분석。결과전성54가의원삼가료감측，종뇨액표본중총공분리출12420주병원균，검출솔배재전5위적의차시대장애희균（46．5％）、시장구균（7．0％）、폐염극뢰백균（5．8％）、분장구균（5．7％）、동록가단포균（3．7％）。대장애희균、폐염극뢰백균、동록가단포균대아알배남적내약솔분별위16．0％、16．7％、15．2％；대좌양불사성적내약솔분별위55．2％、28．2％、27．7％。시장구균화분장구균대만고매소적내약솔분별위4．1％화1．4％。결론뇨로감염주요병원균잉이대장애희균화장구균위주，림상응근거약민시험결과선용항균약물。
Objective To investigate the bacterial distribution and drug resistance in urinary tract infection from Sichuan Provin‐cial Antimicrobial Resistant Investigation Net during 2011-2012 .Methods The distribution and drug resistance data of pathogens isolated from urine specimens of urinary tract infection cases were collected from the members of Sichuan Provincial Antimicrobial Resistant Investigation Net ,and the results were counted and analyzed .Results There were 54 hospitals enrolling in the investiga‐tion .A total of 12 420 pathogenic strains were isolated from urinary tract infection in the survey .The top 5 predominant bacteria were Escherichia coli(46 .5% ) ,Excrement enterococcus (7 .0% ) ,K lebsiella pneumoniae (5 .8% ) ,Dung enterococcus (5 .7% ) and Pseudomonas aeruginosa(3 .7% ) .The resistant rates of Escherichia coli ,K lebsiella pneumoniae and Pseudomonas aeruginosa to imipenem were 16 .0% ,16 .7% and 16 .0% ,and to levofloxacin were 55 .2% ,28 .2% and 27 .7% ,respectively .The resistant rates of Excrement enterococcus and Dung enterococcus to vancomycin were 4 .1% and 1 .4% respectively .Conclusion Escherichiacoli and Enterococcus are still the predominant organism in urinary tract infection cases .Clinical treatment should refer to the results of drug sensitive test .