中国卫生产业
中國衛生產業
중국위생산업
CHINA HEALTH INDUSTRY
2014年
30期
12-13
,共2页
氟尿嘧啶%奥沙利铂%晚期胃癌%联合亚叶酸钙
氟尿嘧啶%奧沙利鉑%晚期胃癌%聯閤亞葉痠鈣
불뇨밀정%오사리박%만기위암%연합아협산개
Fluorouracil%Oxaliplatin into%Advanced gastric cancer%Combined calcium and folic acid
目的：通过氟尿嘧啶、奥沙利铂联合亚叶酸钙治疗晚期胃癌的效果，确定其疗效以及安全性。方法将我院2013年3月-2014年4月入院的42例患者随机分为观察组和对照组各21例，通过用药的不同分析奥沙利铂、氟尿嘧啶联合亚叶酸钙的疗效及安全性。结果通过4个周期疗效发现观察组有效率为76.1%，高于对照组的42.8%，且对照组处于3~4度间的不良反应高于观察组，白细胞减少发生概率对照组为9.52%，观察组为7.14%，贫血对照组为4.76%，观察组为2.38%，神经毒性发生概率对照组要为9.52%，观察组为7.14%观察组为对照组明显高于观察组。结论奥沙利铂、氟尿嘧啶联合亚叶酸钙对于晚期胃癌的治疗疗效好，安全性高，值得推广。
目的：通過氟尿嘧啶、奧沙利鉑聯閤亞葉痠鈣治療晚期胃癌的效果，確定其療效以及安全性。方法將我院2013年3月-2014年4月入院的42例患者隨機分為觀察組和對照組各21例，通過用藥的不同分析奧沙利鉑、氟尿嘧啶聯閤亞葉痠鈣的療效及安全性。結果通過4箇週期療效髮現觀察組有效率為76.1%，高于對照組的42.8%，且對照組處于3~4度間的不良反應高于觀察組，白細胞減少髮生概率對照組為9.52%，觀察組為7.14%，貧血對照組為4.76%，觀察組為2.38%，神經毒性髮生概率對照組要為9.52%，觀察組為7.14%觀察組為對照組明顯高于觀察組。結論奧沙利鉑、氟尿嘧啶聯閤亞葉痠鈣對于晚期胃癌的治療療效好，安全性高，值得推廣。
목적：통과불뇨밀정、오사리박연합아협산개치료만기위암적효과，학정기료효이급안전성。방법장아원2013년3월-2014년4월입원적42례환자수궤분위관찰조화대조조각21례，통과용약적불동분석오사리박、불뇨밀정연합아협산개적료효급안전성。결과통과4개주기료효발현관찰조유효솔위76.1%，고우대조조적42.8%，차대조조처우3~4도간적불량반응고우관찰조，백세포감소발생개솔대조조위9.52%，관찰조위7.14%，빈혈대조조위4.76%，관찰조위2.38%，신경독성발생개솔대조조요위9.52%，관찰조위7.14%관찰조위대조조명현고우관찰조。결론오사리박、불뇨밀정연합아협산개대우만기위암적치료료효호，안전성고，치득추엄。
Objective Through fluorouracil, oxaliplatin into joint and the effect of folic acid, calcium treatment of advanced gastric cancer, determine the efficacy and safety. Methods From March 2013 to April 2013 of 42 cases of hospitalized patients were ran-domly divided into observation group and control group 21 people, through the analysis of the different drugs oxaliplatin into joint, fluorouracil, leucovorin calcium efficacy and safety. Results The curative effect is found through four cycle group effective rate was 76.1%, 42.8%higher than that of control group, and the control group in the adverse reactions between 3 to 4 degrees higher than the observation group, white blood cells reduce probability in the control group was 9.52%, the observation group was 7.14%, ane-mia in the control group was 4.76%, the observation group was 2.38%, the nerve toxicity probability in the control group was 9.52%, as 7.14%group was a control observation group was obviously higher than that of group. Conclusion Oxaliplatin into joint, fluorouracil, leucovorin calcium in the treatment of advanced gastric cancer good curative effect, high safety, is worth promoting.
