CAJ | 학술논문

目的：探讨阿希米联合阿奇霉素治疗宫颈支原体感染的临床疗效。方法：2013年1月-2014年8月收治宫颈支原体感染患者100例，所有患者支原体培养均阳性，随机分成对照组和观察组各50例，对照组治疗方法：阿奇霉素0.5%+0.9%氯化钠注射液250 mL静滴，1次/d，连续治疗7 d，观察组在对照组的基础上于晚睡前阴道内置入阿希米1粒，1次/d，连续放置7次。结果：疗程结束后观察组症状和体征消失49例(98.0%)，支原体培养转阴48例，阴转率96.0%；对照组疗程结束后症状和体征消失30例(60.0%)，支原体培养转阴25例，阴转率50.0%，两组比较差异有统计学意义(P＜0.05)。观察组痊愈45例，有效4例，无效1例，总有效率98.0%；对照组痊愈33例，有效8例，无效9例，总有效率82.0%，两组比较差异有统计学意义(P＜0.05)。结论：阿希米、阿奇霉素联合用药可以明显改善宫颈支原体感染患者的症状，治愈率高，值得临床推广。
목적：탐토아희미연합아기매소치료궁경지원체감염적림상료효。방법：2013년1월-2014년8월수치궁경지원체감염환자100례，소유환자지원체배양균양성，수궤분성대조조화관찰조각50례，대조조치료방법：아기매소0.5%+0.9%록화납주사액250 mL정적，1차/d，련속치료7 d，관찰조재대조조적기출상우만수전음도내치입아희미1립，1차/d，련속방치7차。결과：료정결속후관찰조증상화체정소실49례(98.0%)，지원체배양전음48례，음전솔96.0%；대조조료정결속후증상화체정소실30례(60.0%)，지원체배양전음25례，음전솔50.0%，량조비교차이유통계학의의(P＜0.05)。관찰조전유45례，유효4례，무효1례，총유효솔98.0%；대조조전유33례，유효8례，무효9례，총유효솔82.0%，량조비교차이유통계학의의(P＜0.05)。결론：아희미、아기매소연합용약가이명현개선궁경지원체감염환자적증상，치유솔고，치득림상추엄。
Objective:To explore the curative effect of asimi combined with azithromycin on treatment of cervical mycoplasma infection.Methods:100 patients with cervical mycoplasma infection were selected from January 2013 to August 2014.All patients with mycoplasma culture were positive.They were randomly divided into the control group and the observation group with 50 cases in each group.The treatment of the control group was with azithromycin 0.5% plus NS 250 mL for intravenous infusion,1 time/day, for 7 days.The observation group were treated with 1 capsule asimi into the vagina before going to bed on the basis of the control group,1 time/d,for 7 days.Results:After the treatment,in the observation group,the symptoms and signs were disappeared in 49 cases(98% );mycoplasma culture was negative in 48 cases,and negative conversion rate was 96% .In the control group,the symptoms and signs were disappeared in 30 cases(60%);mycoplasma culture was negative in 25 cases,and negative conversion rate was 50% .The difference was statistically significant(P<0.05).In the observation group,45 cases were cured;4 cases were effective;1 case was invalid;the total effective rate was 98%.In the control group,33 cases were cured;8 cases were effective;9 cases were invalid;the total efficiency was 82%.The difference was statistically significant(P<0.05).Conclusion:Asimi combined with azithromycin can obviously improve the symptoms of patients with cervical mycoplasma infection.The cure rate is high,and it is worthy of clinical application.