中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
33期
75-76
,共2页
卡介菌多糖核酸%喘息型支气管炎%预防与治疗
卡介菌多糖覈痠%喘息型支氣管炎%預防與治療
잡개균다당핵산%천식형지기관염%예방여치료
BCG polysaccharide and nucleic acid%Asthmatic bronchitis%Prevention and treatment
目的：探讨卡介菌多糖核酸治疗喘息型支气管炎(简称喘支)患儿喘息的临床疗效及价值。方法：2009年2月-2011年2月收治支气管哮喘患儿84例，住院治愈后随机分成两组：预防组40例，出院后进行卡介菌多糖核酸1 mL肌注；对照组44例，出院后不进行任何防治，均跟踪随访2年，观察并比较两组患儿喘息复发情况及喘息时持续时间。结果：预防组2年内喘息复发率20%，发作频率平均(1.88±0.227)次，发作喘息时持续时间平均(2.46±0.194) h；对照组2年内喘息复发率59%，发作频率平均(2.04±0.216)次，发作喘息时持续时间平均(2.80±0.21)h；两组对比差异具有统计学意义(P＜0.05)。结论：卡介菌多糖核酸具有预防喘支患儿复发的作用，且有缩短发作频率及发作时持续时间。
目的：探討卡介菌多糖覈痠治療喘息型支氣管炎(簡稱喘支)患兒喘息的臨床療效及價值。方法：2009年2月-2011年2月收治支氣管哮喘患兒84例，住院治愈後隨機分成兩組：預防組40例，齣院後進行卡介菌多糖覈痠1 mL肌註；對照組44例，齣院後不進行任何防治，均跟蹤隨訪2年，觀察併比較兩組患兒喘息複髮情況及喘息時持續時間。結果：預防組2年內喘息複髮率20%，髮作頻率平均(1.88±0.227)次，髮作喘息時持續時間平均(2.46±0.194) h；對照組2年內喘息複髮率59%，髮作頻率平均(2.04±0.216)次，髮作喘息時持續時間平均(2.80±0.21)h；兩組對比差異具有統計學意義(P＜0.05)。結論：卡介菌多糖覈痠具有預防喘支患兒複髮的作用，且有縮短髮作頻率及髮作時持續時間。
목적：탐토잡개균다당핵산치료천식형지기관염(간칭천지)환인천식적림상료효급개치。방법：2009년2월-2011년2월수치지기관효천환인84례，주원치유후수궤분성량조：예방조40례，출원후진행잡개균다당핵산1 mL기주；대조조44례，출원후불진행임하방치，균근종수방2년，관찰병비교량조환인천식복발정황급천식시지속시간。결과：예방조2년내천식복발솔20%，발작빈솔평균(1.88±0.227)차，발작천식시지속시간평균(2.46±0.194) h；대조조2년내천식복발솔59%，발작빈솔평균(2.04±0.216)차，발작천식시지속시간평균(2.80±0.21)h；량조대비차이구유통계학의의(P＜0.05)。결론：잡개균다당핵산구유예방천지환인복발적작용，차유축단발작빈솔급발작시지속시간。
Objective: To investigate the clinical efficacy and value of BCG polysaccharide nucleic acid in treatment of asthmatic bronchitis(referred to as asthmatic bronchitis) in children with wheezing.Methods:84 children with bronchial asthma were selected from February 2009 to February 2011.They were randomly divided into two groups after hospitalization curing:40 cases in the prevention group,we gave them BCG polysaccharide nucleic acid injection 1ml after discharge;44 cases in the control group,they were not given any treatment after discharged.They were followed up for 2 years,and we observed and compared the asthmatic recurrence situation and the duration of breath of the two groups.Results:The asthmatic recurrence rate of the prevention group in the 2 years was 20%;the mean seizure frequency was(1.88±0.227)time;the average continuous time when the asthmatic attack was(2.46 ± 0.194)h.The asthmatic recurrence rate of the control group in the 2 years was 59% ;the mean seizure frequency was(2.04 ± 0.216)time;the average continuous time when the asthmatic attack was(2.80 ± 0.21)h.There has the significant difference between the two groups(P<0.05).Conclusion:BCG polysaccharide nucleic acid has the effect to prevent relapse in children with asthmatic bronchitis,and it can short the attack continuous time and seizure frequency.
