CAJ | 학술논문

目的：探讨老老年高血压患者不同舒张压水平低密度脂蛋白的特征。方法选择老老年高血压患者259例，均询问病史、行常规生化检查和动态血压监测；按照24 h 平均舒张压水平分组：1组≥80 mmHg（1 mmHg ＝0．133 kPa），2组70～79 mmHg，3组60～69 mmHg，4组50～59 mmHg，5组＜50 mmHg；比较不同动态舒张压水平低密度脂蛋白水平。结果低密度脂蛋白水平1组（3．27±0．69）mmol／L，2组（2．48±0．56）mmol／L，3组（2．70±0．57） mmol／L，4组（2．67±0．63）mmol／L，5组（2．82±0．62）mmol／L，其中2组低密度脂蛋白水平最低，1，5组显著高于2，3，4组（P 均＜0．05），5组低密度脂蛋白水平由低到高依次为2组＜4组＜3组＜5组＜1组。结论老老年高血压患者舒张压水平宜控制在70～79 mmHg，低密度脂蛋白水平最低，提示24 h 平均舒张压70～79 mmHg 或许可以成为老老年高血压患者舒张压的合理范围；舒张压过高和过低预后均较差。
목적：탐토로노년고혈압환자불동서장압수평저밀도지단백적특정。방법선택로노년고혈압환자259례，균순문병사、행상규생화검사화동태혈압감측；안조24 h 평균서장압수평분조：1조≥80 mmHg（1 mmHg ＝0．133 kPa），2조70～79 mmHg，3조60～69 mmHg，4조50～59 mmHg，5조＜50 mmHg；비교불동동태서장압수평저밀도지단백수평。결과저밀도지단백수평1조（3．27±0．69）mmol／L，2조（2．48±0．56）mmol／L，3조（2．70±0．57） mmol／L，4조（2．67±0．63）mmol／L，5조（2．82±0．62）mmol／L，기중2조저밀도지단백수평최저，1，5조현저고우2，3，4조（P 균＜0．05），5조저밀도지단백수평유저도고의차위2조＜4조＜3조＜5조＜1조。결론로노년고혈압환자서장압수평의공제재70～79 mmHg，저밀도지단백수평최저，제시24 h 평균서장압70～79 mmHg 혹허가이성위로노년고혈압환자서장압적합리범위；서장압과고화과저예후균교차。
Objective It is to approach the low -density lipoprotein characteristic in very elderly hypertensive patients with different levels of diastolic blood pressure.Methods 259 hospitalized cases of very elderly hypertensive patients were se-lected and asked about the history, routine biochemical tests and ambulatory blood pressure monitoring; then divided them ac-cordance with the 24 -hour average diastolic pressure level: group 1 with levels of ≥ 80 mmHg, group 2 set of 70 to79 mm-Hg, group 3 set of 60 to 69 mmHg, group 4 set of 50 to 59 mmHg, group 5 set of <50 mmHg; the levels of LDL of different dynamic diastolic blood pressure were compared.Results The level of LDL was (3.27 ±0.69) mmol/L of group 1,(2.48 ± 0.66) mmol/L of group 2, (2.70 ±0.77) mmol/L of group 3, (2.67 ±0.83) mmol/L of group 4 and (2.82 ±0.62) mmol/L of group 5 respectively; the level of LDL in group 2 was the minimum; the LDL levels of group 1 and 5 were higher than those of group 2, 3, 4 (all P <0.05); the LDL level of five groups from low to high for the group 2 <group 4 <group 3 <group 5 <group 1.Conclusion The level of diastolic blood pressure in patients with hypertension should be controlled at 70 to 79 mmHg, the level of LDL is the lowest; this prompt that 24 -hour mean diastolic blood pressure of 70 to 79 mmHg could become very elderly hypertensive patients with diastolic reasonable range, and the diastolic blood pressure of too high and too low will be a poor prognosis.