CAJ | 학술논문

目的：对生化检验项目用于肝硬化疾病诊断中的临床价值进行分析，进而为临床检验和诊断提供参考依据。方法选取从2013年3月～2014年6月收治的50例肝硬化患者，并选取同期的50例健康体检者，对其进行有关生化指标的检测，对比分析检测结果。结果在血清透明质酸、Ⅲ型前胶原、层黏连蛋白以及Ⅳ型胶原方面，肝硬化组明显高于对照组，P＜0.05，其差异有统计学意义。肝硬化组在天冬氨酸氨基转移酶、丙氨酸氨基转移酶、碱性磷酸酶、γ-谷氨酰转肽酶、总胆红素以及直接胆红素方面，与健康组相比较明显升高，P＜0.05，其差异有统计学意义；在胆碱酯酶、总蛋白、白蛋白方面，与健康组相比较明显降低， P＜0.05，其差异有统计学意义。结论检测肝脏各项生化指标，可以为肝硬化的临床诊断提供参考依据。
목적：대생화검험항목용우간경화질병진단중적림상개치진행분석，진이위림상검험화진단제공삼고의거。방법선취종2013년3월～2014년6월수치적50례간경화환자，병선취동기적50례건강체검자，대기진행유관생화지표적검측，대비분석검측결과。결과재혈청투명질산、Ⅲ형전효원、층점련단백이급Ⅳ형효원방면，간경화조명현고우대조조，P＜0.05，기차이유통계학의의。간경화조재천동안산안기전이매、병안산안기전이매、감성린산매、γ-곡안선전태매、총담홍소이급직접담홍소방면，여건강조상비교명현승고，P＜0.05，기차이유통계학의의；재담감지매、총단백、백단백방면，여건강조상비교명현강저， P＜0.05，기차이유통계학의의。결론검측간장각항생화지표，가이위간경화적림상진단제공삼고의거。
Objective To analyze the clinical values of biochemical examination in the diagnosis of hepatic sclerosis, and to provide reference for clinical examination and diagnosis.Methods 50 cases of hepatic sclerosis from March 2013 to June 2014 were selected, 50 cases of healthy volunteers from the same period were also selected as control, the biochemical indexes were examined and analyzed.Results HA、PC-Ⅲ、IV-C、LN、DBIL、TBIL、γ-GT、ALP、ALT and AST were signiifcantly higher, comparing with the control group, P<0.05, there were statistically signiifcant difference between groups, and CHE、TP、ALB were decreased,P<0.05, there were statistically signiifcant difference between groups.Conclusion Detecting the biomedical indexes of hepatic sclerosis could provide reference for the clinical diagnosis and have the value of clinical application.