CAJ | 학술논문

目的：探讨影响老年急性肾衰竭( ARF)患者预后的因素。方法对解放军白求恩国际和平医院干部病房2005年1月—2013年1月住院的412例老年ARF的临床资料进行回顾性分析。结果412例ARF中,感染、心力衰竭、肾毒性药物、肿瘤、手术为导致老年ARF的常见原因(分别占38.4%、21.6%、18.0%、9.0%、6.1%)。单因素分析提示,感染、应用肾毒性药物、心力衰竭、高龄(≥80岁)、合并多器官功能不全综合征( MODS)、有慢性肾脏病史与老年ARF患者的预后密切相关(P<0．01,P<0．05)。 logistic回归分析显示,感染、应用肾毒性药物、心力衰竭、高龄(≥80岁)、合并多器官功能障碍综合征(MODS)是影响老年ARF患者预后的独立危险因素(P<0．05)。结论应充分重视影响老年ARF预后的相关因素,及时给予针对性治疗,以降低病死率、改善预后。
목적：탐토영향노년급성신쇠갈( ARF)환자예후적인소。방법대해방군백구은국제화평의원간부병방2005년1월—2013년1월주원적412례노년ARF적림상자료진행회고성분석。결과412례ARF중,감염、심력쇠갈、신독성약물、종류、수술위도치노년ARF적상견원인(분별점38.4%、21.6%、18.0%、9.0%、6.1%)。단인소분석제시,감염、응용신독성약물、심력쇠갈、고령(≥80세)、합병다기관공능불전종합정( MODS)、유만성신장병사여노년ARF환자적예후밀절상관(P<0．01,P<0．05)。 logistic회귀분석현시,감염、응용신독성약물、심력쇠갈、고령(≥80세)、합병다기관공능장애종합정(MODS)시영향노년ARF환자예후적독립위험인소(P<0．05)。결론응충분중시영향노년ARF예후적상관인소,급시급여침대성치료,이강저병사솔、개선예후。
Objective To investigate the influencing factors of the prognosis in elderly patients with acute renal failure ( ARF) . Methods Clinical data of 412 elderly patients with ARF during January 2005 and January 2013 was ret-rospectively analyzed. Results The common causes of induced ARF in the 412 elderly patients were infection, heart failure, application of renal toxicity drugs, tumor and surgery, and the corresponding rates were 38. 4%, 21. 6%, 18. 0%, 9. 0% and 6. 1% respectively. The single factor analysis showed that infection, application of renal toxicity drugs, heart failure, aged (≥80 years old) , complication of MODS ( multiple organ dysfunction syndrome) and history of chronic renal disease were closely related with prognosis (P <0. 01, P <0. 05). The Logistic Regression Analysis showed that infection, application of renal toxicity drugs, heart failure, aged (≥80 years old) and complication of MODS were independent risk factors of the prognosis in elderly patients with ARF (P<0. 05). Conclusion Influencing factors of prognosis should be given more attention in elderly patients with ARF, and pertinent treatment should be taken to re-duce mortality rate and improve prognosis.