CAJ | 학술논문

目的：研究多发性骨髓瘤的骨髓形态学特征，探讨骨髓形态学在多发性骨髓瘤诊断中的临床应用价值。方法对广东医学院附属医院63例多发性骨髓瘤病人进行骨髓涂片及细胞染色和进行检验诊断分析。结果94％的患者骨髓增生度都达到增生活跃以上，只有6％的是增生低下或极度低下，瘤细胞数量﹥15％，根据形态可分为四类；病人骨髓其他系包括巨核系、粒系、红系和淋巴系细胞都不同程度减少和受抑制。结论骨髓形态学分析是多发性骨髓瘤诊断和治疗疗效监测具有重要的临床应用价值，具有广泛开展的必要性和意义。
목적：연구다발성골수류적골수형태학특정，탐토골수형태학재다발성골수류진단중적림상응용개치。방법대엄동의학원부속의원63례다발성골수류병인진행골수도편급세포염색화진행검험진단분석。결과94％적환자골수증생도도체도증생활약이상，지유6％적시증생저하혹겁도저하，류세포수량﹥15％，근거형태가분위사류；병인골수기타계포괄거핵계、립계、홍계화림파계세포도불동정도감소화수억제。결론골수형태학분석시다발성골수류진단화치료료효감측구유중요적림상응용개치，구유엄범개전적필요성화의의。
Objective The study on the morphological features of bone marrow of multiple myeloma and discussion the clinical use of bone marrow morphology in the diagnosis of multiple myeloma .Method Analysis of affiliated hospital of guangdong medical college in 63 cases on multiple myeloma patients bone marrow smears and cell staining and laboratory diagnostic .Results More than 94%of patients with bone marrow hyperplasia get active proliferation and only 6%of patients with low proliferation or extremely low proliferation.The number of tumor cells'less than 15% in these patients.According to the form, it can be divided into four types, including bone marrow megakaryocytic , myeloid, elytroid and lymphoid cells. In this study , these cells were decreased and restrained in patients . Conclusion Bone marrow morphology analysis which as a good tool for the diagnosis of multiple myeloma and the assay of therapeutic effects is important for these applications in the further .