CAJ | 학술논문

目的：评估自制的便携式封闭负压引流（vacuum sealing drainage，VSD）装置对家猪爆炸伤模型创面的引流效果。方法遴选市售健康5～6个月龄家猪4头，雌雄各半，体质量35～40 kg，将雷管植入双侧后肢肌肉组织发达处，制造8个爆炸创面，配对分成观察组和对照组。在室外暴露创面4 h后进行清创，观察组给予彻底清创，VSD装置处理；对照组彻底清创后，无菌纱布覆盖。分别于暴露创面4h，治疗3、7d后对伤口大体判断疗效，观察白细胞、表皮生长因子的变化。结果爆炸4h后，两组实验对象白细胞、表皮生长因子的变化差异无统计学意义（P＞0．05）；治疗3、7 d后，观察组白细胞、表皮生长因子明显高于对照组，差异有统计学意义（P＜0．05）。观察组伤口大体判断疗效观察较对照组创面清洁、无异味，触之易出血，创面有大量的颗粒状肉芽组织，创面周缘无明显的水肿和继发性坏死组织。结论自制便携式封闭负压引流装置在家猪爆炸创面愈合方面效果显著，且装置体积小、携带方便，可进一步应用于临床护理实践验证。
목적：평고자제적편휴식봉폐부압인류（vacuum sealing drainage，VSD）장치대가저폭작상모형창면적인류효과。방법린선시수건강5～6개월령가저4두，자웅각반，체질량35～40 kg，장뢰관식입쌍측후지기육조직발체처，제조8개폭작창면，배대분성관찰조화대조조。재실외폭로창면4 h후진행청창，관찰조급여철저청창，VSD장치처리；대조조철저청창후，무균사포복개。분별우폭로창면4h，치료3、7d후대상구대체판단료효，관찰백세포、표피생장인자적변화。결과폭작4h후，량조실험대상백세포、표피생장인자적변화차이무통계학의의（P＞0．05）；치료3、7 d후，관찰조백세포、표피생장인자명현고우대조조，차이유통계학의의（P＜0．05）。관찰조상구대체판단료효관찰교대조조창면청길、무이미，촉지역출혈，창면유대량적과립상육아조직，창면주연무명현적수종화계발성배사조직。결론자제편휴식봉폐부압인류장치재가저폭작창면유합방면효과현저，차장치체적소、휴대방편，가진일보응용우림상호리실천험증。
Objective To evaluate the effect of new patent of self-made portable vacuum sealing drainage device in animal experiment blast inj ury wounds drainage.Methods 4 pigs with two male and two female, body weight 35~40 kg were selected and implant the detonator in the developed muscle tissue of hind limbs,and made 8 blast inj ury wound,and paring into observation group and control group.The wounds were exposed outdoor and debride the wounds after 4 h.The observation group was given thorough debridement with VSD treatment;the control group was treated with sterile gauze covered after thorough debridement.The wounds healing situation and the change of white blood cells,epidermal growth factor were observed respectively at 4h after wounds exposed,3d and 7d after treatment.Results There were no significant differences between the change of two groups of pig’s white blood cells and epidermal growth factors after 4 hours of expose of wounds(P>0.05).The white blood cells and epidermal growth factor observed after treatment of 3 days and 7 days of observation group was significantly higher than which in control group(P<0.05).Comparing with control group,the observation group had clean surface of the wound with no smell,easy to bleeding,large amount of granular granulation tissue,no obvious edema at wound periphery and secondary necrotic tissue.Conclusion The portable vacuum sealing drainage device had significant effect in this animal nursing practice research of blast inj ury wounds healing.The device is small and easy to carry which can be further verified in clinical nursing practice.