CAJ | 학술논문

目的：分析奥美拉唑胃溃疡合并出血的疗效，探讨其临床适用性。方法：选择胃溃疡合并出血的患者68例，随机分为试验组和对照组，各组34例。对照组采用常规治疗，试验组在常规治疗的基础上联合奥美拉唑治疗。观察治疗过程中两组患者的止血时间、临床疗效及不良反应情况，随访患者治疗后的复发情况。结果：试验组患者平均止血时间为（6．5±2．5） d，对照组为（9．1±2．9） d，差异有统计学意义（P＜0．05）；治疗后试验组患者的总有效率为97．1％，而对照组为76．5％，差异有统计学意义（P＜0．05）；试验组患者不良反应发生率为8．8％，对照组为5．9％，差异无统计学意义（P＞0．05）；试验组患者复发率8．8％，明显低于对照组32．4％，差异有统计学意义（P＜0．05）。结论：联合奥美拉唑治疗胃溃疡合并出血具有良好的临床疗效，可明显降低止血时间和复发率，且用药安全，适合临床推广应用。
목적：분석오미랍서위궤양합병출혈적료효，탐토기림상괄용성。방법：선택위궤양합병출혈적환자68례，수궤분위시험조화대조조，각조34례。대조조채용상규치료，시험조재상규치료적기출상연합오미랍서치료。관찰치료과정중량조환자적지혈시간、림상료효급불량반응정황，수방환자치료후적복발정황。결과：시험조환자평균지혈시간위（6．5±2．5） d，대조조위（9．1±2．9） d，차이유통계학의의（P＜0．05）；치료후시험조환자적총유효솔위97．1％，이대조조위76．5％，차이유통계학의의（P＜0．05）；시험조환자불량반응발생솔위8．8％，대조조위5．9％，차이무통계학의의（P＞0．05）；시험조환자복발솔8．8％，명현저우대조조32．4％，차이유통계학의의（P＜0．05）。결론：연합오미랍서치료위궤양합병출혈구유량호적림상료효，가명현강저지혈시간화복발솔，차용약안전，괄합림상추엄응용。
Objective To analyze the effect of omeprazole in the treatment of ulcer joint hemorrhage.Methods Select 68 cases of ulcer joint hemorrhage,and they were simply randomly divided into experimental group and control group,the control group received conventional treatment,while the test group combined with omeprazole.Observed the bleeding time,the clinical efficacy and adverse reactions,the recurrence after treatment.Results The average Bleeding time of the test group was (6. 5 ±2. 5 ) days,while of the control group was (9. 1 ±2. 9)days,the difference was statistically significant.The total effective rate of the test group was 97. 1%after treatment,while was 76. 5% in the control group,the difference was statistically significant,the occurrence of adverse reaction of the test group was 8. 8%,while was 5. 9% in the control group,the difference was not statistically significance.The recurrence rate of the test group was 8. 8%,while was 32. 4%in the control group,the difference was statistically significant.Conclusion Ome-prazole in the treatment of ulcer joint hemorrhage has good clinical efficacy,and reduces bleeding time and recurrence rates,and drug safety,is suitable for long-term clinical application.