中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
7期
839-843
,共5页
黄海蓉%叶兆嘉%青柳潔%田添英明
黃海蓉%葉兆嘉%青柳潔%田添英明
황해용%협조가%청류결%전첨영명
跌倒相关疾病%髋部骨折%病例对照研究
跌倒相關疾病%髖部骨摺%病例對照研究
질도상관질병%관부골절%병례대조연구
Fall-related disease%Hip fracture%Case-control study
目的:探讨中老年妇女跌倒相关疾病和髋部骨折的关系。方法研究对象为日本长崎县国民健康保险的参保者。收集45岁以上妇女髋部骨折住院患者1109例,按年龄配比随机抽取1109名其他患者,进行病例对照研究。髋部骨折和跌到相关疾病根据国际疾病分类标准编码第十版( ICD-10)进行判定。卡方检验用于比较两组患者跌倒相关疾病的患病率差,条件Logistic回帰分析用于分析跌倒相关疾病与髋部骨折的关联性。结果75%以上的髋部骨折患者的年龄大于80岁。髋部骨折患者的视力障碍(14.25%vs.8.66%, P <0.001),脑卒中(14.07%vs.9.92%, P =0.002),肌肉骨骼疾病(43.91%vs.38.77%,P<0.001),帕金森氏病(5.86%vs.1.53%,P<0.001),认知障碍(11.45%vs.4.33%,P<0.001)和抑郁症(13.89%vs.5.86%,P<0.001)的患病率显著高于对照组。这些疾病的髋部骨折相对危险度分别为:视力障碍1.49(95%CI:1.13,1.98)、脑卒中1.29(95%CI:0.98,1.69)、肌肉骨骼疾病1.29(95%CI:1.08,1.54)、帕金森氏病3.33(95%CI:1.87,5.92)、认知障碍2.46(95%CI:1.72,3.52)和抑郁症2.09(95%CI:1.54,2.85)。合并的跌倒相关疾病越多,髋部骨折风险越大。结论在中老年妇女,跌倒相关疾病与髋部骨折有显著的关联性。积极预防和治疗跌倒相关疾病可能有益于降低髋部骨折的发生危险。
目的:探討中老年婦女跌倒相關疾病和髖部骨摺的關繫。方法研究對象為日本長崎縣國民健康保險的參保者。收集45歲以上婦女髖部骨摺住院患者1109例,按年齡配比隨機抽取1109名其他患者,進行病例對照研究。髖部骨摺和跌到相關疾病根據國際疾病分類標準編碼第十版( ICD-10)進行判定。卡方檢驗用于比較兩組患者跌倒相關疾病的患病率差,條件Logistic迴帰分析用于分析跌倒相關疾病與髖部骨摺的關聯性。結果75%以上的髖部骨摺患者的年齡大于80歲。髖部骨摺患者的視力障礙(14.25%vs.8.66%, P <0.001),腦卒中(14.07%vs.9.92%, P =0.002),肌肉骨骼疾病(43.91%vs.38.77%,P<0.001),帕金森氏病(5.86%vs.1.53%,P<0.001),認知障礙(11.45%vs.4.33%,P<0.001)和抑鬱癥(13.89%vs.5.86%,P<0.001)的患病率顯著高于對照組。這些疾病的髖部骨摺相對危險度分彆為:視力障礙1.49(95%CI:1.13,1.98)、腦卒中1.29(95%CI:0.98,1.69)、肌肉骨骼疾病1.29(95%CI:1.08,1.54)、帕金森氏病3.33(95%CI:1.87,5.92)、認知障礙2.46(95%CI:1.72,3.52)和抑鬱癥2.09(95%CI:1.54,2.85)。閤併的跌倒相關疾病越多,髖部骨摺風險越大。結論在中老年婦女,跌倒相關疾病與髖部骨摺有顯著的關聯性。積極預防和治療跌倒相關疾病可能有益于降低髖部骨摺的髮生危險。
목적:탐토중노년부녀질도상관질병화관부골절적관계。방법연구대상위일본장기현국민건강보험적삼보자。수집45세이상부녀관부골절주원환자1109례,안년령배비수궤추취1109명기타환자,진행병례대조연구。관부골절화질도상관질병근거국제질병분류표준편마제십판( ICD-10)진행판정。잡방검험용우비교량조환자질도상관질병적환병솔차,조건Logistic회귀분석용우분석질도상관질병여관부골절적관련성。결과75%이상적관부골절환자적년령대우80세。관부골절환자적시력장애(14.25%vs.8.66%, P <0.001),뇌졸중(14.07%vs.9.92%, P =0.002),기육골격질병(43.91%vs.38.77%,P<0.001),파금삼씨병(5.86%vs.1.53%,P<0.001),인지장애(11.45%vs.4.33%,P<0.001)화억욱증(13.89%vs.5.86%,P<0.001)적환병솔현저고우대조조。저사질병적관부골절상대위험도분별위:시력장애1.49(95%CI:1.13,1.98)、뇌졸중1.29(95%CI:0.98,1.69)、기육골격질병1.29(95%CI:1.08,1.54)、파금삼씨병3.33(95%CI:1.87,5.92)、인지장애2.46(95%CI:1.72,3.52)화억욱증2.09(95%CI:1.54,2.85)。합병적질도상관질병월다,관부골절풍험월대。결론재중노년부녀,질도상관질병여관부골절유현저적관련성。적겁예방화치료질도상관질병가능유익우강저관부골절적발생위험。
Objective To study the correlation between fall-related diseases and hip fracture among the elderly women.Methods A total of 1109 women, who were over 45 years old and had hip fractures, were identified from health insurance claims in Nagasaki Prefecture in Japan.At the same time, a age-matched ( within 5-year age groups) control patient was randomly selected for each patient with hip fracture.Diseases such as hip fracture and the fall-related diseases were coded following the International Classification of Diseases, 10th Revision ( ICD-10 ) .The prevalence of visual impairment, stroke, musculoskeletal diseases, Parkinson’ s disease, cognitive impairment, depression, and the number of these risk factors were compared between patients with hip fractures and controls using the Chi-square test.The strength of the association between risk factors and hip fracture was estimated using a conditional Logistic regression model.Results Over 75% women with hip fracture were over 80 years old. Women with hip fracture had a significantly higher prevalence of ocular diseases ( 14.25% vs.8.66%, P <0.001 ) , stroke (14.07%vs.9.92%, P=0.002), musculoskeletal diseases (43.91% vs.38.77%, P<0.001), Parkinson’s disease (5.86%vs.1.53%, P<0.001), cognitive impairment (11.45%vs.4.33%, P<0.001), and depression (13.89%vs.5.86%, P<0. 001) than those in controls.The results of conditional Logistic regression showed that ocular diseases (OR=1.49, 95%CI:1.13, 1.98), stroke (OR=1.29, 95%CI:0.98, 1.69), musculoskeletal diseases (OR=1.29, 95% CI:1.08, 1.54), Parkinson’s disease (OR=3.33, 95%CI:1.87, 5.92), cognitive impairment (OR=2.46, 95% CI:1.72, 3.52), and depression (OR=2.09, 95%CI:1.54, 2.85) were significantly associated with hip fracture.Women with multiple risk factors were at higher risk of the hip fractures.Conclusion Fall-related diseases play an important role in hip fracture among the middle-aged and elderly women.Positive prevention and treatment of the fall-related diseases may contribute to lower the risks of hip fracture.