CAJ | 학술논문

目的：探讨罗哌卡因配伍小剂量氯胺酮自控硬膜外镇痛用于分娩镇痛的临床效果。方法选择自愿接受分娩镇痛单胎初产妇130例，随机将其分为观察组与对照组，每组各65例。产程开始后，观察组注射罗哌卡因配伍小剂量氯胺酮，对照组仅注射罗哌卡因，观察两组产妇的镇痛效果、产程时间、缩宫素使用情况、分娩方式、产后2h出血量以及新生儿情况等。结果给药后1h、2h两组产妇疼痛程度比较差异有统计学意义（ P<0.05）；两组在顺产率、器械助产率、剖宫产率和催产素使用率方面比较，差异均无统计学意义（ P>0.05）。结论罗哌卡因配伍小剂量氯胺酮在自控硬膜外分娩镇痛中的应用是安全、有效的，可以减轻产妇的痛苦并且对母婴无不良反应，值得在临床上推广和应用。
목적：탐토라고잡인배오소제량록알동자공경막외진통용우분면진통적림상효과。방법선택자원접수분면진통단태초산부130례，수궤장기분위관찰조여대조조，매조각65례。산정개시후，관찰조주사라고잡인배오소제량록알동，대조조부주사라고잡인，관찰량조산부적진통효과、산정시간、축궁소사용정황、분면방식、산후2h출혈량이급신생인정황등。결과급약후1h、2h량조산부동통정도비교차이유통계학의의（ P<0.05）；량조재순산솔、기계조산솔、부궁산솔화최산소사용솔방면비교，차이균무통계학의의（ P>0.05）。결론라고잡인배오소제량록알동재자공경막외분면진통중적응용시안전、유효적，가이감경산부적통고병차대모영무불량반응，치득재림상상추엄화응용。
Objective To investigate the clinical effect of ropivacaine combined With loW -dose Ketamine controlled epidural analgesia for labor analgesia. Methods 130 singletons primipara voluntarily adopted labor analgesia Were randomly divided into observation group and control group With 65 cases in each group. Cases in observation group Were given ropivacaine combined With loW-dose Ketamine,cases in control group Were given ropivacaine. The analgesic effect,duration of labor,oXytocin usage,mode of delivery,postpartum 2h hemorrhage amount,and neonatal condition Were observed. Results The difference of pain degree of puerpera 1h,2h after administration betWeen tWo groups had statistical significance(P<0. 05). The difference of vaginal delivery rate, instrumental delivery rate,caesarean section rate,oXytocin use rate betWeen tWo groups had no statistical significance( P>0. 05 ). Conclusion The ropivacaine combined With loW-dose Ketamine controlled epidural analgesia for labor analgesia is safe and effective Which can alleviate the suffering of maternal Without adverse reactions.