中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
8期
930-935
,共6页
肝肾阴虚%综合疗效%评价指标%骨质疏松症%权重系数
肝腎陰虛%綜閤療效%評價指標%骨質疏鬆癥%權重繫數
간신음허%종합료효%평개지표%골질소송증%권중계수
The liver and the kidney Yin deficiency%Comprehensive curative effect%Index of evaluation%Osteoporosis%Weight coefficient
目的：观察肝肾阴虚型骨质疏松症患者治疗前后各指标的变化，运用各指标的权重系数对其中期疗效进行综合评价，探讨一种新的评价方法。方法通过文献检索及临床观察，纳入60例肝肾阴虚型骨质疏松症患者，补益肝肾治疗加基础钙剂。采用专家调查形式对各指标进行权重系数划定，观察治疗前、治疗5个月后疼痛和中医主要症状、体征评分，骨代谢生化指标（β－CrossLaps、P1NP）、骨密度指标的检测值，从而确定疗效等级，评价其5个月后的疗效以及各指标前后的变化。结果各指标的权重系数分别为：疼痛28％、中医症状体征28％、P1NP15．3％、β－CrossLaps6．7％、L2－L4椎体BMD22％。其中以综合权重评分分值＞23．8％为治愈，13．4％～23．8％为好转，＜13．4％为未愈，各指标治疗前后均有变化。结论对于一种多指标评价体系，可以运用权重系数方法进行综合评价，值得临床推广。
目的：觀察肝腎陰虛型骨質疏鬆癥患者治療前後各指標的變化，運用各指標的權重繫數對其中期療效進行綜閤評價，探討一種新的評價方法。方法通過文獻檢索及臨床觀察，納入60例肝腎陰虛型骨質疏鬆癥患者，補益肝腎治療加基礎鈣劑。採用專傢調查形式對各指標進行權重繫數劃定，觀察治療前、治療5箇月後疼痛和中醫主要癥狀、體徵評分，骨代謝生化指標（β－CrossLaps、P1NP）、骨密度指標的檢測值，從而確定療效等級，評價其5箇月後的療效以及各指標前後的變化。結果各指標的權重繫數分彆為：疼痛28％、中醫癥狀體徵28％、P1NP15．3％、β－CrossLaps6．7％、L2－L4椎體BMD22％。其中以綜閤權重評分分值＞23．8％為治愈，13．4％～23．8％為好轉，＜13．4％為未愈，各指標治療前後均有變化。結論對于一種多指標評價體繫，可以運用權重繫數方法進行綜閤評價，值得臨床推廣。
목적：관찰간신음허형골질소송증환자치료전후각지표적변화，운용각지표적권중계수대기중기료효진행종합평개，탐토일충신적평개방법。방법통과문헌검색급림상관찰，납입60례간신음허형골질소송증환자，보익간신치료가기출개제。채용전가조사형식대각지표진행권중계수화정，관찰치료전、치료5개월후동통화중의주요증상、체정평분，골대사생화지표（β－CrossLaps、P1NP）、골밀도지표적검측치，종이학정료효등급，평개기5개월후적료효이급각지표전후적변화。결과각지표적권중계수분별위：동통28％、중의증상체정28％、P1NP15．3％、β－CrossLaps6．7％、L2－L4추체BMD22％。기중이종합권중평분분치＞23．8％위치유，13．4％～23．8％위호전，＜13．4％위미유，각지표치료전후균유변화。결론대우일충다지표평개체계，가이운용권중계수방법진행종합평개，치득림상추엄。
Objective To observe the changes of indicators in patients with the liver and the kidney Yin deficiency osteoporosis before and after the treatment, and to investigate a new evaluation method by using the weight coefficient of each index to comprehensively evaluate the curative effect.Methods By literature retrieval and clinical observation, 60 patients with the liver and the kidney Yin deficiency osteoporosis were selected.All the patients were given the tonifying the liver and the kidney treatment with calcium supplements.Each index weight coefficient was defined according to expert survey form.Pain, main symptoms and signs according to traditional Chinese medicine, bone metabolic biochemical index (β-CrossLaps and P1NP), and bone mineral density ( BMD) were determined before and 5 months after the treatment, in order to determine the grade of the curative effect.The changes of the indexes before and 5 months after treatment were also evaluated.Results The weight coefficient of pain, symptoms and signs according to traditional Chinese medicine, P1NP, β-CrossLaps, BMD of L2-L4 was 28%, 28%, 15.3%, 6.7%, and 22%, respectively.The comprehensive weighted score over 23.8% was considered as cured, 13.4% -23.8% was considered as improved, and below 13.4%was considered as non-cured.Various indicators changed before and after the treatment. Conclusion As a multi-index evaluation system, using the weight coefficient method can make a comprehensive evaluation, which is worthy of clinical promotion.
