CAJ | 학술논문

目的：初步探讨绝经后妇女骨密度与血红蛋白、血小板的相关性。方法随机选择319例福州常住汉族绝经后妇女，分为骨质疏松组147例，非骨质疏松组172例，双能X线骨密度仪测定腰椎、股骨颈、大转子和Ward’ s区骨密度，SPSS 18．0统计软件分析血红蛋白、血小板与不同部位骨密度的关系。结果（1）与非骨质疏松组相比，骨质疏松组患者的血红蛋白含量更高（z＝－3．099，P＝0．002），血小板计数更多（z＝－3．436，P＝0．001）。（2）校正年龄、体重指数和绝经年限后，血小板与腰椎、大转子骨密度呈负相关（r1＝－0．189，P1＝0．001；r2＝－0．146，P2＝0．009）；血红蛋白与腰椎、大转子骨密度也呈负相关（r1＝－0．133，P1＝0．018；r2＝－0．200，P2＝0．000）。（3）多元逐步回归分析显示，血红蛋白与大转子骨密度呈负相关（β＝－0．183，P＝0．000）；血小板与腰椎骨密度呈负相关（β＝－0．182，P＝0．001）。结论绝经后妇女低骨量的发生与血红蛋白、血小板均存在负相关，鉴于与当前部分结果并不一致，故仍需进一步深入探究。
목적：초보탐토절경후부녀골밀도여혈홍단백、혈소판적상관성。방법수궤선택319례복주상주한족절경후부녀，분위골질소송조147례，비골질소송조172례，쌍능X선골밀도의측정요추、고골경、대전자화Ward’ s구골밀도，SPSS 18．0통계연건분석혈홍단백、혈소판여불동부위골밀도적관계。결과（1）여비골질소송조상비，골질소송조환자적혈홍단백함량경고（z＝－3．099，P＝0．002），혈소판계수경다（z＝－3．436，P＝0．001）。（2）교정년령、체중지수화절경년한후，혈소판여요추、대전자골밀도정부상관（r1＝－0．189，P1＝0．001；r2＝－0．146，P2＝0．009）；혈홍단백여요추、대전자골밀도야정부상관（r1＝－0．133，P1＝0．018；r2＝－0．200，P2＝0．000）。（3）다원축보회귀분석현시，혈홍단백여대전자골밀도정부상관（β＝－0．183，P＝0．000）；혈소판여요추골밀도정부상관（β＝－0．182，P＝0．001）。결론절경후부녀저골량적발생여혈홍단백、혈소판균존재부상관，감우여당전부분결과병불일치，고잉수진일보심입탐구。
Objective To investigate the relationship between bone mineral density (BMD), hemoglobin (HGB), and platelet ( PLT) in postmenopausal women.Methods A total of 319 postmenopausal Han women, who lived in Fuzhou, were randomly selected and divided into osteoporosis group ( OP group, 147 cases) and non-osteoporosis group ( NOP group, 172 cases) .BMD of the lumbar vertebrae, the femoral neck, the greater trochanter, and the Ward ’ s area was detected using dual energy X-ray absorptiometry.The correlation between BMD of different parts, HGB, and PLT was analyzed using a SPSS 18.0 statistical software.Results Compared with those in the NOP group, the hemoglobin level ( z=-3.099, P=3.099) and platelet count ( z=-3.436, P=0.001) in OP group were higher.After adjusting for age, body mass index (BMI), and duration of menopause, PLT was negatively correlated with BMD of the lumbar vertebrae and the greater trochanter ( r1 =-0.189, P1 =0.001; r2 =-0.146, P2 =0.009).HGB was also negatively correlated with BMD of the lumbar vertebrae and the greater trochanter (r1 =-0.133, P1 =0.018;r2 =-0.200, P2 =0.000) .Multiple stepwise regression analysis showed that HGB was negatively correlated with BMD of the greater trochanter (β=-0.183, P=0.000).PLT was negatively correlated with BMD of the lumbar vertebrae (β=-0.182, P=0.001) .Conclusion The occurrence of low bone mass in postmenopausal women is negatively correlated with HGB and PLT.This result is not consistent with several current results, therefore, further study is needed.