CAJ | 학술논문

目的：探讨金因肽联合半导体激光治疗复发性口腔溃疡的临床效果。方法将100例复发性口腔溃疡患者随机分为实验组和对照组各50例。对照组使用金因肽1喷/次，3次/d；实验组在对照组的基础上增加半导体激光的照射治疗，照射6 min/次，1次/d，对两组疼痛消失、溃疡愈合和复发率情况进行对比。结果疼痛消失的时间实验组(2.99±0.35)d，对照组(4.33±0.47)d，两组比较差异有统计学意义(P＜0.05)；溃疡愈合时间实验组(4.60±0.75)d，对照组(6.38±0.76)d，两组比较差异有统计学意义(P＜0.05)；口腔溃疡的复发率实验组4.00%，对照组16.00%，两组比较差异有统计学意义(P＜0.05)。结论金因肽联合半导体激光治疗复发性口腔溃疡可以缩短疼痛和愈合时间，减少复发频率，具有应用价值。
목적：탐토금인태연합반도체격광치료복발성구강궤양적림상효과。방법장100례복발성구강궤양환자수궤분위실험조화대조조각50례。대조조사용금인태1분/차，3차/d；실험조재대조조적기출상증가반도체격광적조사치료，조사6 min/차，1차/d，대량조동통소실、궤양유합화복발솔정황진행대비。결과동통소실적시간실험조(2.99±0.35)d，대조조(4.33±0.47)d，량조비교차이유통계학의의(P＜0.05)；궤양유합시간실험조(4.60±0.75)d，대조조(6.38±0.76)d，량조비교차이유통계학의의(P＜0.05)；구강궤양적복발솔실험조4.00%，대조조16.00%，량조비교차이유통계학의의(P＜0.05)。결론금인태연합반도체격광치료복발성구강궤양가이축단동통화유합시간，감소복발빈솔，구유응용개치。
Objective To conduct the clinical observation on rhEGF com bined w ith sem iconductor laser to treat recurrent oral ulcer. Methods 100 cases w ith recurrent oral ulcer w ere random ly divided into experim ental group and control group w ith 50 cases in each group.The control group w ere given a spray of rhEG F for 3 tim es a day.The experim ental group,on the basis of the control group thera-py,w ere plus treated w ith sem iconductor laser irradiation of 6 m inutes once a day.Then the pain disappearance,healing situation of ulcer and recurrence rate in both groups w ere com pared .R esults The pain disappearance tim e in the experim ental group and the control group w ere(2.99±0.35)days and (4.33±0.47)days respectively,and the differences betw een the tw o groups w ere of statistical significance(P<0.05).The healing tim e of ulcer in the experim ental group and the control group w ere(4.60±0.75)days and(6.38±0.76)days respective-ly,and the differences betw een the tw o groups w ere of statistical significance(P<0.05).The recurrence rate of oral ulcer in the experim en-tal group and the control group w ere 4 .00% and 16 .00% ,and the differences betw een the tw o groups w ere of statistical significance (P<0 .05 ).Conclusion rhEGF com bined w ith sem iconductor laser to treat recurrent oral ulcer can shorten the pain and healing tim e,reduce the recurrence rate,w hich has application values.